FlyBase Allele Report: Dmel\Amun[GD9779]

General Information

Symbol

Dmel\Amun^GD9779

Species

D. melanogaster

Name

FlyBase ID

FBal0202307

Feature type

allele

Associated gene

Dmel\Amun

Associated Insertion(s)

Carried in Construct

P{GD9779}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD9779}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD9779

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

eye, with Scer\GAL4^ey.3.5.Exel

(Shalaby et al., 2009)

macrochaeta & mesothoracic tergum, with Scer\GAL4^ptc-559.1

(Shalaby et al., 2009)

macrochaeta & mesothoracic tergum, with Scer\GAL4^sca-537.4

(Shalaby et al., 2009)

macrochaeta & mesothoracic tergum | ectopic, with Scer\GAL4^ptc-559.1

(Shalaby et al., 2009)

macrochaeta & mesothoracic tergum | ectopic, with Scer\GAL4^sca-537.4

(Shalaby et al., 2009)

macrochaeta & mesothoracic tergum | supernumerary, with Scer\GAL4^ptc-559.1

(Shalaby et al., 2009)

macrochaeta & mesothoracic tergum | supernumerary, with Scer\GAL4^sca-537.4

(Shalaby et al., 2009)

mesothoracic tergum, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

microchaeta & mesothoracic tergum, with Scer\GAL4^pnr-MD237

(Shalaby et al., 2009)

microchaeta & mesothoracic tergum, with Scer\GAL4^sr-md710

(Shalaby et al., 2009)

trichogen cell, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Detailed Description

Statement

Reference

Adults expressing Amun^GD9779 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

Expression under the control of Scer\GAL4^pnr-MD237 results in a colour difference between the central Scer\GAL4^pnr-MD237 expression domain of the notum and the surrounding lateral region in 100% of the Scer\GAL4^pnr-MD237 expression domain.

Expression under the control of Scer\GAL4^pnr-MD237 results in bristle morphology defects on the notum in 100% of the Scer\GAL4^pnr-MD237 expression domain.

Expression under the control of Scer\GAL4^pnr-MD237 results in the absence of 40-50% of the Scer\GAL4^pnr-MD237-expressing area of the notum.

(Mummery-Widmer et al., 2009)

Expression of Amun^GD9779 under the control of Scer\GAL4^ey.3.5.Exel reduces eye size.

Expression of Amun^GD9779 (together with Dcr-2^GD11939) under the control of Scer\GAL4^sca-537.4 or Scer\GAL4^ptc-559.1 results in multiple bristle defects including missing, supernumerary, and misplaced macrochaetae, as well as probable shaft-to-socket transformations.

Expression of Amun^GD9779 (together with Dcr-2^GD11939) under the control of Scer\GAL4^sr-md710 or Scer\GAL4^pnr-MD237 results in disorganized and smaller microchaetae.

(Shalaby et al., 2009)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development