UASt regulatory sequences drive expression of an inverted repeat.
100% of flies expressing HeximGD10991 under the control of Scer\GAL4rn-GAL4-5 have undeveloped wings and legs.
95.8% of animals expressing HeximGD10991 under the control of Scer\GAL4lz-gal4 die as pupae. The remaining 4.2% are viable, but have eye defects.
44.2% of flies expressing HeximGD10991 under the control of Scer\GAL4GMR.PU have black-spotted eyes, while the remaining 55.8% have rough eyes.
Adults expressing HeximGD10991 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in early larval lethality or late larval lethality.
Expression under the control of Scer\GAL4Mef2.PR results in grossly normal larval body wall muscles.
Expression under the control of Scer\GAL4Mef2.PR results in wild-type sarcomeres in the larval body wall muscles.
Expression under the control of Scer\GAL4pnr-MD237 results in lethality (either before or at the pupal stage), depending on the insertion line used.
HeximGD10991 is partially rescued by Scer\GAL4rn-GAL4-5/HeximUAS.cNa
HeximGD10991 is partially rescued by Scer\GAL4lz-gal4/HeximUAS.cNa
HeximGD10991 is partially rescued by Scer\GAL4ptc-559.1/HeximUAS.cNa
HeximGD10991 is partially rescued by Scer\GAL4GMR.PU/HeximUAS.cNa
Co-expression of HeximScer\UAS.cNa partially rescues the mutant phenotypes caused by expression of HeximGD10991 under the control of one of Scer\GAL4rn-GAL4-5, Scer\GAL4lz-gal4, Scer\GAL4GMR.PU or Scer\GAL4ptc-559.1.