UASt regulatory sequences drive expression of an inverted repeat.
Expression of Glut1GD4552 (together with UAS-Dicer2 to enhance RNAi efficiency) under the control of Scer\GAL4GMR.PU has no effect on adult eye appearance.
Adults expressing Glut1GD4552 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) can show significantly reduced avoidance of noxious temperature (46[o]C) compared to control flies, depending on the particular P{GD4552} insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 may result in semi-lethality, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 0% or 50-60% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 0% or 50-60% of the Scer\GAL4pnr-MD237-expressing area of the notum, depending on the insertion line used.
Glut1GD4552, Scer\GAL4GMR.PU is an enhancer of visible | adult stage phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PU
Glut1GD4552, Scer\GAL4GMR.PU is an enhancer of eye | adult stage phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PU
The moderate rough eye phenotype and reduced adult eye size characteristic for flies expressing Scer\GAL4GMR.PU under the control of Hsap\MAPTV337M.Scer\UAS is significantly worsened by co-expression of Glut1GD4552 (together with UAS-Dicer2 to enhance RNAi efficiency), exacerbating the rough appearance.