UASt regulatory sequences drive expression of an inverted repeat.
Expression of Sema2aGD5476 under the control of Scer\GAL4VGlut-OK371 does not affect adult walking pattern.
Adults expressing Sema-2aGD5476 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Scer\GAL4peb-GAL4, Sema-2a[+]/Sema2a03474, Sema2aGD5476, Sema2bunspecified has abnormal neuroanatomy | adult stage phenotype
Scer\GAL4peb-GAL4, Sema-2a[+]/Sema2a03474, Sema2aGD5476, Sema2bunspecified has adult antennal lobe projection neuron phenotype
Sema-2a03474/+ Sema-2bunspecified/Sema-2bunspecified flies show a small but significant ventromedial shift of Mmus\Cd8aMz19-positive projection neuron dendrite targeting. There is an additional significant ventromedial shift for these dendrites if the flies are also expressing Sema-2aGD5476 under the control of Scer\GAL4peb-GAL4.