UASt regulatory sequences drive expression of an inverted repeat.
Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.
Adults expressing cmGD10049 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in late pupal lethality.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 90-100% of the Scer\GAL4pnr-MD237-expressing area of the notum.
Expression of cmGD10049 under the control of Scer\GAL4Bx-MS1096 results in small and curly wings.
Expression of cmGD10049 under the control of Scer\GAL4ey.PH and Scer\GAL4GMR.PF results in a rough eye phenotype.
Scer\GAL4GMR.PF, Scer\GAL4ey.PH, cmGD10049 has partially lethal - majority die | female phenotype
Scer\GAL4GMR.PF, Scer\GAL4ey.PH, cmGD10049 has lethal | male phenotype
Scer\GAL4GMR.PF, Scer\GAL4ey.PH, cmGD10049 has eye phenotype
Coexpression of Dcr-2Scer\UAS.cDa with cmGD10049, under the control of Scer\GAL4ey.PH and Scer\GAL4GMR.PF, results in male lethality and female lethality to a lesser extent. This coexpression also results in small eyes. None of these phenotypes are observed when only cmGD10049 is expressed with this driver.
Coexpression of Dcr-2Scer\UAS.cDa with cmGD10049, under the control of Scer\GAL4Bx-MS1096, results in lethality and defects in thorax closure. These phenotypes are not seen when only cmGD10049 is expressed with this driver.