FB2024_03 , released June 25, 2024
Allele: Dmel\ospGD1504
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General Information
Symbol
Dmel\ospGD1504
Species
D. melanogaster
Name
FlyBase ID
FBal0210268
Feature type
allele
Associated gene
Dmel\osp
Associated Insertion(s)
Carried in Construct
P{GD1504}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
in vitro construct
(Dickson et al., 2007.7.18)
Progenitor genotype
Carried in construct
P{GD1504}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD1504
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults expressing ospGD1504 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

      (Neely et al., 2010)

      Expression of ospGD1504 under the control of Scer\GAL4Bx-MS1096 results in curly and dusky wings.

      Expression of ospGD1504 under the control of Scer\GAL4pnr-MD237 results in a defective thorax closure phenotype.

      (Dietzl et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4pnr-MD237, ospGD1504 has thorax phenotype, enhanceable by Dcr-2UAS.cDa, Scer\GAL4pnr-MD237

      (Dietzl et al., 2007)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Coexpression of Dcr-2Scer\UAS.cDa with ospGD1504, under the control of Scer\GAL4ey.PH and Scer\GAL4GMR.PF, results in a rough eye phenotype in addition to the defective eye color phenotype that is seen when only ospGD1504 is expressed with these drivers.

      Coexpression of Dcr-2Scer\UAS.cDa with ospGD1504, under the control of Scer\GAL4pnr-MD237, results in an enhancement of the defective thorax closure phenotype of ospGD1504 flies, and additionally causes male lethality and partial female lethality.

      (Dietzl et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ospGD1504
      Name Synonyms
      Secondary FlyBase IDs
        References (6)