UASt regulatory sequences drive expression of an inverted repeat.
The expression of fzrGD9960 under the control of Scer\GAL4ey.PU results in high lethality and leads to eye defects, including retina and eye size reductions, as compared to controls; expression under the control of Scer\GAL4GMR.PU leads to a strong roughness of the whole eye, as compared to controls.
Adults expressing rapGD9960 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) can show significantly reduced avoidance of noxious temperature (46[o]C) compared to control flies, depending on the particular P{GD9960} insertion line used.
Expression under the control of Scer\GAL4Mef2.PR results in semi-lethality.
Expression under the control of Scer\GAL4pnr-MD237 results in external sensory organs consisting of empty or multiple sockets in 10-20% of the Scer\GAL4pnr-MD237 expression domain of the notum.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 0% or 60-70% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
fzrGD9960, Scer\GAL4ey.PU is a suppressor | partially of abnormal size | adult stage phenotype of CycAGD8653, Scer\GAL4ey.PU
fzrGD9960, Scer\GAL4ey.PU is a suppressor | partially of visible | adult stage phenotype of CycAGD8653, Scer\GAL4ey.PU
fzrGD9960, Scer\GAL4tin.CΔ4 is a suppressor of abnormal endomitotic cell cycle phenotype of RafAct.UAS, Scer\GAL4tin.CΔ4
fzrGD9960, Scer\GAL4tin.CΔ4 is a suppressor of abnormal endomitotic cell cycle phenotype of Hsap\RAF1gof.UAS, Scer\GAL4tin.CΔ4
fzrGD9960, Scer\GAL4ey.PU is a suppressor | partially of eye phenotype of CycAGD8653, Scer\GAL4ey.PU
fzrGD9960, Scer\GAL4tin.CΔ4 is a suppressor of cardial cell phenotype of RafAct.UAS, Scer\GAL4tin.CΔ4
fzrGD9960, Scer\GAL4tin.CΔ4 is a suppressor of cardial cell phenotype of Hsap\RAF1gof.UAS, Scer\GAL4tin.CΔ4
The co-expression of fzrGD9960 partially suppresses the small eyes induced by the expression of CycAGD8653 under the control of Scer\GAL4ey.PU.
The cardiac specific expression of rapGD9960 under the control of Scer\GAL4tin.CΔ4 prevents the phlAct.Scer\UAS-induced increases in cardiomyocyte ploidy.
The cardiac specific expression of rapGD9960 under the control of Scer\GAL4tin.CΔ4 prevents the Hsap\RAF1gof.Scer\UAS-induced increases in cardiomyocyte ploidy.