UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing slprGD9771 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4pnr-MD237 may result in semi-lethality, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in loss of bristles on the notum in 20-30% of the Scer\GAL4pnr-MD237 expression domain.
Expression under the control of Scer\GAL4pnr-MD237 results in mild thorax closure defects.
Dcr-2UAS.cDa, Scer\GAL4pnr-MD237, slprGD9771 has lethal phenotype
Dcr-2UAS.cDa, Scer\GAL4GMR.PF, Scer\GAL4ey.PH, slprGD9771 has eye phenotype
There is a significant reduction in chromosome instability tolerance induced by mad2GD16427 expression, when slprGD9771 is expressed in imaginal wing discs under the control of Scer\GAL4en.PU or Scer\GAL4hh.PU.
Coexpression of Dcr-2Scer\UAS.cDa with slprGD9771, under the control of Scer\GAL4ey.PH and Scer\GAL4GMR.PF, results in small and rough eye phenotypes, which are not seen when slprGD9771 alone is expressed.
Coexpression of Dcr-2Scer\UAS.cDa with slprGD9771, under the control of Scer\GAL4pnr-MD237, results in lethality, although expression of slprGD9771 alone with this driver does not affect survival.