UASt regulatory sequences drive expression of an inverted repeat.
Expression of stumpsGD10225 in retinal basal glial (RBG) cell clones under the control of Scer\GAL4repo results in a reduction in RBG cell number, loss of differentiation and lack of migration in third instar larvae.
Expression of stumpsGD10225 driven by Scer\GAL4elav.PLu does not significantly affect the number of boutons per muscle at the neuromuscular junction of third instar larvae, compared to controls.
Adults expressing stumpsGD10225 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in late pupal lethality.
Expression of stumpsGD10225 under the control of Scer\GAL4repo results in a 52% reduction in glial cell number in the eye disc.
Scer\GAL4how-24B, stumpsGD10225 has some die during P-stage phenotype, enhanceable by SmnRNAi.C.UAS.WIZ/Scer\GAL4how-24B
Scer\GAL4how-24B/stumpsGD10225 is an enhancer of some die during P-stage phenotype of Scer\GAL4how-24B, SmnRNAi.C.UAS.WIZ
Co-expression of stumpsGD10225 enhances pupal lethality in Scer\GAL4how-24B>SmndsRNA.C.Scer\UAS.WIZ flies (and vice versa).