FB2024_03 , released June 25, 2024
Allele: Dmel\taiGD4265
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General Information
Symbol
Dmel\taiGD4265
Species
D. melanogaster
Name
FlyBase ID
FBal0210727
Feature type
allele
Associated gene
Dmel\tai
Associated Insertion(s)
Carried in Construct
P{GD4265}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
in vitro construct
(Dickson et al., 2007.7.18)
Progenitor genotype
Carried in construct
P{GD4265}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD4265
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of taiGD4265 under the control of Scer\GAL4221 results in a reduced dendritic arborization in third instar larval class I abdominal dorsal multidendritic ddaD and ddaE neurons, as compared to controls; expression under the control of Scer\GAL4ppk.PG, in combination with Dicer-2 for efficient RNAi, results in no obvious dendrite morphology defects in abdominal dorsal multidendritic ddaD neurons, as compared to controls.

      (Hattori et al., 2013)

      Expression of taiGD4265 under the control of either Scer\GAL4ptc-559.1 or Scer\GAL4bab1-Pgal4-2 in the somatic cells of the germarium (using the temperature sensitive Scer\GAL80ts.αTub84B allele to restrict expression to the adult stage) results in supernumerary germline cells containing a single spectrosome.

      (König et al., 2011)
      External Data
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 1 )
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      taiGD4265
      Name Synonyms
      Secondary FlyBase IDs
        References (7)