FlyBase Allele Report: Scer\GAL4[bab1-Pgal4-2]

Drives expression in the terminal filament of the germarium; and in somatic cells of the ovary; in both male and female genital discs; in male germline cysts; and in the larval proventriculus; also drives expression in regions corresponding to sub-terminal structures in imaginal discs.

(FlyBase Curators, 2017)

ScerGAL4^bab1-Pgal4-2 drives expression in in apical cells (germarium cap cells and terminal filaments) of germarium region 1.

(Hartman et al., 2010)

Marker for

Reflects expression of

bab1

(Hartman et al., 2010, Guo and Wang, 2009, Cabrera et al., 2002)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell migration | prepupal stage, with bab2^GD17091

(Green and Extavour, 2012)

abnormal cell number | oogenesis, with hh^UAS.cUa

(Çiçek et al., 2016)

abnormal cell number | oogenesis, with Rab23^UAS.cCa

(Çiçek et al., 2016)

abnormal cell number | prepupal stage, with bab2^GD17091

(Green and Extavour, 2012)

abnormal cell shape | oogenesis, with hh^UAS.cUa

(Çiçek et al., 2016)

abnormal cell shape | oogenesis, with Rab23^UAS.cCa

(Çiçek et al., 2016)

decreased cell number | adult stage | conditional, with dpp^RNAi.UASp

(Wang et al., 2011)

female sterile, with zfh1^KK109931

(Lobell et al., 2017)

hyperplasia, with boi^GD60

(Hartman et al., 2010)

hyperplasia, with boi^ΔFN1.UAS, boi^e01708

(Hartman et al., 2010)

increased cell number | adult stage | female, with Mmp2^NIG.1794-1R

(Wang and Page-McCaw, 2014)

increased occurrence of cell division | adult stage | female, with boi^GD60

(Hartman et al., 2010)

increased occurrence of cell division | adult stage | female, with Mmp2^NIG.1794-1R

(Wang and Page-McCaw, 2014)

increased occurrence of cell division | oogenesis, with hh^UAS.cUa

(Çiçek et al., 2016)

increased occurrence of cell division | oogenesis, with Rab23^UAS.cCa

(Çiçek et al., 2016)

neoplasia | adult stage | female, with Scer\GAL4^C587, hh^TRiP.cUa

(Li et al., 2015)

Phenotype Manifest In

arista, with lin^GD1479

(Greenberg and Hatini, 2009)

basal cylinder, with lin^GD1479

(Greenberg and Hatini, 2009)

basal stalk, with hh^UAS.cUa

(Çiçek et al., 2016)

basal stalk, with Rab23^UAS.cCa

(Çiçek et al., 2016)

female germline cell | increased number, with EcR^A.UAS

(König et al., 2011)

female germline cell | increased number, with EcR^B1.UAS

(König et al., 2011)

female germline stem cell, with dally^GD5918

(Guo and Wang, 2009)

female germline stem cell, with dpp^RNAi.UASp

(Wang et al., 2011)

female germline stem cell | increased number, with dally^UAS.cJa

(Guo and Wang, 2009)

follicle cell, with boi^GD60

(Hartman et al., 2010)

follicle cell, with hh^UAS.cUa

(Çiçek et al., 2016)

follicle cell, with Rab23^UAS.cCa

(Çiçek et al., 2016)

follicle stem cell, with boi^GD60

(Hartman et al., 2010)

follicle stem cell, with boi^ΔFN1.UAS, boi^e01708

(Hartman et al., 2010)

germarium, with dpp^RNAi.UASp

(Wang et al., 2011)

germarium, with Scer\GAL4^C587, hh^TRiP.cUa

(Li et al., 2015)

germarium cap cell | increased number, with EcR^A.UAS

(König et al., 2011)

germarium cap cell | increased number, with EcR^B1.UAS

(König et al., 2011)

germarium region 2b, with Mmp2^NIG.1794-1R

(Wang and Page-McCaw, 2014)

germline cell | increased number | heat sensitive, with EcR^RNAi.UAS.cCa, Scer\GAL80^ts.αTub84B

(König et al., 2011)

germline cell | increased number | heat sensitive, with Scer\GAL80^ts.αTub84B, tai^GD4265

(König et al., 2011)

nurse cell, with hh^UAS.cUa

(Çiçek et al., 2016)

nurse cell, with Rab23^UAS.cCa

(Çiçek et al., 2016)

ovariole, with CG31999^KK102256

(Lobell et al., 2017)

ovariole, with Mdr49^KK106585

(Lobell et al., 2017)

ovariole, with RhoGEF64C^KK103071

(Lobell et al., 2017)

ovariole, with SdhA^KK101728

(Lobell et al., 2017)

ovary, with dpp^RNAi.UASp

(Wang et al., 2011)

ovary, with zfh1^KK109931

(Lobell et al., 2017)

prothoracic tarsal segment, with lin^GD1479

(Greenberg and Hatini, 2009)

sex comb, with lin^GD1479

(Greenberg and Hatini, 2009)

stalk follicle cell, with boi^GD60

(Hartman et al., 2010)

stalk follicle cell, with hh^UAS.cUa

(Çiçek et al., 2016)

stalk follicle cell, with Rab23^UAS.cCa

(Çiçek et al., 2016)

stalk follicle cell | increased number, with Mmp2^JF01337

(Wang and Page-McCaw, 2014)

stalk follicle cell | increased number, with Mmp2^NIG.1794-1R

(Wang and Page-McCaw, 2014)

terminal filament | prepupal stage, with bab2^GD17091

(Green and Extavour, 2012)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

ihog^G13202/Scer\GAL4^bab1-Pgal4-2 is a suppressor of hyperplasia phenotype of boi^e01708

(Hartman et al., 2010)

hh^JF01804/Scer\GAL4^bab1-Pgal4-2 is a suppressor of hyperplasia phenotype of boi^e01708

(Hartman et al., 2010)

Phenotype Manifest In

Suppressor of

Statement

Reference

hh^JF01804/Scer\GAL4^bab1-Pgal4-2 is a suppressor of follicle stem cell phenotype of boi^e01708

(Hartman et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

jar^UAS.GFP/Scer\GAL4^bab1-Pgal4-2 partially rescues jar¹

(Isaji et al., 2011)

dally^UAS.cJa/Scer\GAL4^bab1-Pgal4-2 partially rescues dally^gem

(Guo and Wang, 2009)

Fails to rescue

vret^UASp.Tag:MYC/Scer\GAL4^bab1-Pgal4-2 fails to rescue vret^148-60

(Zamparini et al., 2011)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

6803

w^*; P{GawB}bab1^Pgal4-2/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Scer\GAL4^bab1-Pgal4-2

bab1^Pgal4-2

(Li et al., 2016)

bab1Gal4^Pgal4-2

(Wang and Page-McCaw, 2014)

Name Synonyms

Secondary FlyBase IDs

References (24)

Report Sections

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