FlyBase Allele Report: Dmel\hh[JF01804]

General Information

Symbol

Dmel\hh^JF01804

Species

D. melanogaster

Name

FlyBase ID

FBal0219821

Feature type

allele

Associated gene

Dmel\hh

Associated Insertion(s)

Carried in Construct

P{TRiP.JF01804}

Also Known As

hh^RNAi, UAS-hh^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.1.15)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.1.15)

Mutagen

in vitro construct

(Perkins et al., 2009.1.15)

Progenitor genotype

Carried in construct

P{TRiP.JF01804}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.1.15)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF01804

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased fecundity | female, with Scer\GAL4^GMR42B09

(Allbee et al., 2018)

Phenotype Manifest In

ovariole | adult stage, with Scer\GAL4^GMR42B09

(Allbee et al., 2018)

ovary | adult stage, with Scer\GAL4^GMR42B09

(Allbee et al., 2018)

Detailed Description

Statement

Reference

Expressing hh^JF01804 under the control of Scer\GAL4^GMR42B09 induces mild ovary defects and females lay significantly fewer eggs than controls.

(Allbee et al., 2018)

Wing patterning is not significantly affected when hh^JF01804 is driven by Scer\GAL4^nub-AC-62.

(Im et al., 2015)

Expressing hh^JF01804 under the control of Scer\GAL4^ey.PH does not cause any overt eye overgrowth.

(Da Ros et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^GMR42B09, hh^JF01804 has decreased fecundity | female phenotype, enhanceable by Ecol\lacZ[+]/Ecol\lacZ^bab-P

(Allbee et al., 2018)

Enhancer of

Statement

Reference

hh^JF01804, Scer\GAL4^ey.PH is an enhancer of visible | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Suppressor of

Statement

Reference

hh^JF01804/Scer\GAL4^NP2222 is a suppressor | partially of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4^NP2222, htl^λ.UAS

(Dong et al., 2021)

hh^JF01804/Scer\GAL4^NP2222 is a suppressor | partially of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^NP2222, htl^λ.UAS

(Dong et al., 2021)

hh^JF01804/Scer\GAL4^bab1-Pgal4-2 is a suppressor of hyperplasia phenotype of boi^e01708

(Hartman et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^GMR42B09, hh^JF01804 has ovary | adult stage phenotype, enhanceable by Ecol\lacZ[+]/Ecol\lacZ^bab-P

(Allbee et al., 2018)

Enhancer of

Statement

Reference

hh^JF01804, Scer\GAL4^ey.PH is an enhancer of eye phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Suppressor of

Statement

Reference

hh^JF01804/Scer\GAL4^NP2222 is a suppressor | partially of neuroblast | larval stage phenotype of Scer\GAL4^NP2222, htl^λ.UAS

(Dong et al., 2021)

hh^JF01804/Scer\GAL4^bab1-Pgal4-2 is a suppressor of follicle stem cell phenotype of boi^e01708

(Hartman et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

hh^JF01804 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. The phenotype is seen with 100% penetrance.

(Da Ros et al., 2013)

Expression of hh^JF01804 in apical follicle cells under the control of Scer\GAL4^bab1-Pgal4-2 suppresses the follicle stem cell hyper-proliferation and excess follicle cell accumulation phenotypes in boi^e01708 mutants.

(Hartman et al., 2010)

Xenogenetic Interactions

Statement

Reference

The mild ovary defects and the decreased egg laying induced by the expression of hh^JF01804 under the control of Scer\GAL4^GMR42B09 are enhanced by one copy of Ecol\lacZ^bab-P.

(Allbee et al., 2018)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

25794

y¹ v¹; P{TRiP.JF01804}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Hh<up>RNAi TRiP</up>

(Allbee et al., 2018)

hh^JF01804

hh^RNAi

(Hartman et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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