FlyBase Allele Report: Dmel\osa[C819]

General Information

Symbol

Dmel\osa^C819

Species

D. melanogaster

Name

FlyBase ID

FBal0216151

Feature type

allele

Associated gene

Dmel\osa

Associated Insertion(s)

P{GSV1}osa^C819

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GSV1}osa^C819

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GSV1}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^dpp.3KK

(Molnar et al., 2006)

visible, with Scer\GAL4^MD-638

(Molnar et al., 2006)

visible, with Scer\GAL4^salm-459.2

(Terriente-Félix and de Celis, 2009)

Phenotype Manifest In

wing cell, with Scer\GAL4^salm-459.2

(Terriente-Félix and de Celis, 2009)

wing vein, with Scer\GAL4^dpp.3KK

(Molnar et al., 2006)

wing vein, with Scer\GAL4^MD-638

(Molnar et al., 2006)

wing vein | ectopic, with Scer\GAL4^salm-459.2

(Terriente-Félix and de Celis, 2009)

Detailed Description

Statement

Reference

The wing shows severe reductions in size, increased extra vein tissue, and loss of intervein territories in a dose-sensitive manner in response to increased levels of osa^C819 under the control of Scer\GAL4^salm-459.2. Severity: Scer\GAL4^salm-459.2; osa^C819 > Scer\GAL4^salm-459.2; osa^C819/+ > Scer\GAL4^salm-459.2/+; osa^C819/+.

(Terriente-Félix and de Celis, 2009)

Expression of C819^C819 under the control of Scer\GAL4^dpp.3KK results in wing vein thickening.

Expression of C819^C819 under the control of Scer\GAL4^MD-638 results in wing vein thickening.

Expression of C819^C819 under the control of Scer\GAL4^sca-C253 does not result in a mutant phenotype.

(Molnar et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

osa^C819/Scer\GAL4^MD-638 is an enhancer of wing vein | ectopic phenotype of bs²

(Terriente-Félix and de Celis, 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Overexpression of osa^C819 by Scer\GAL4^MD-638 enhances the ectopic veins observed in bs² mutant animals.

(Terriente-Félix and de Celis, 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{GSV1} insertion line that when expressed using Scer\GAL4^dpp.3KK results in a mutant phenotype in the wing.

(Molnar et al., 2006)

Separable from: another five P{GSV1} insertions.

(Molnar et al., 2006)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

C819^C819

osa^C819

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close