Expression of GSd458GSd458 under the control of Scer\GAL4109(2)80 results in defects in the dendrites of dorsal cluster dendritic arborisation (da) neurons in third instar larvae: dendrite morphology is defective in the class I and class III da neurons, dendrite growth is reduced in the class II da neurons, and dendrite growth and branching are reduced in the class IV da neurons.
Expression of GSd458GSd458 under the control of Scer\GAL4221 results increased numbers of small dendritic branches in the ddaE da neurons, although the primary branches are unaffected.
Isolated RP2 neuron clones expressing GSd458GSd458 under the control of Scer\GAL4Act5C.PP (clones generated using the Scer\FLP1eve.RN2 line) show altered distribution of dendrites in the dendritic field at 25-31 hours after egg laying: the number of dendrites targeted to medial regions is decreased.
Fas2-positive axon bundles in the ventral nerve cord are seen misplaced within the connective in embryos expressing GSd458GSd458 under the control of Scer\GAL4scrt-11-6.