FB2024_02 , released April 23, 2024
Allele: Scer\GAL4109(2)80
Open Close
General Information
Symbol
Scer\GAL4109(2)80
Species
S. cerevisiae
Name
FlyBase ID
FBal0102847
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GAL4109(2)80, 109(2)80-gal4, md-GAL4, GAL4 109(2)80, 109(2)80, GAL4109(2)80, 109(2)80 Gal4, Gal4 109(2) 80, 109(2)80Gal4
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Allele components
Component
Use(s)
Inserted element
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression in multidendritic and dendritic arborizing neurons.

Scer\GAL4109(2)80 drives expression in all dendritic arborizing neurons in pharate adults.

Scer\GAL4109(2)80 drives expression in the multidendritic neurons of the PNS (bipolar and class I-IV) and in multiple medial and lateral cells of the ventral nerve cord. Expression in the CNS is restricted to a few cells in the brain.

In late embryos, in PNS dorsal clusters of segments A1-A7, Scer\GAL4109(2)80 drives high levels of expression in all 6 md (multidendritic) neurons, one bd (bipolar dendrite) neuron, and one td (tracheal innervating) neuron; expression not observed in es (external sensory) neurons; high levels of expression in PNS lateral and ventral clusters, and in the procephalic neurogenic region.

 
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

dendrite & dendritic arborising neuron, with lvaRNAi.1.UAS

dendritic arborising neuron & dendritic tree, with nanosαTub84B.3'UTR.UAS

filopodium & dendrite, with CaMKIIT287A.UAS

filopodium & dendrite, with CaMKIIT287D.UAS

filopodium & dendrite, with CaMKIIUAS.cKa

filopodium & dendrite, with Rac1UAS.cLa

Golgi apparatus & dendritic arborising neuron, with lvaRNAi.1.UAS

Detailed Description
Statement
Reference

Inhibition (using Ctet\tetXTNT-LC.UAS) of Scer\GAL4109(2)80 cells significantly reduces larval escape behavior in response to HCl application, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
NOT Enhanced by
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference
Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

NakRNAi.UAS, Scer\GAL4109(2)80 has dendrite | larval stage phenotype, enhanceable by Chc[+]/Chc1

NOT Enhanced by
Suppressed by
Statement
Reference

Scer\GAL4109(2)80, nanosαTub84B.3'UTR.UAS has dendritic arborising neuron & dendritic tree phenotype, suppressible | partially by pum1/pum1

NOT suppressed by
Statement
Reference
Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
References (119)