FlyBase Allele Report: Dmel\Mical[N-ter.UAS]

General Information

Symbol

Dmel\Mical^N-ter.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0242679

Feature type

allele

Associated gene

Dmel\Mical

Associated Insertion(s)

Carried in Construct

P{UAS-Mical.N-ter}

Also Known As

UAS-Mical^NT, UAS-Mical^N-ter

Key Links

Transgenic product class

inframe_deletion

(Kirilly et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Kirilly et al., 2009)

Mutagen

in vitro construct

(Kirilly et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-Mical.N-ter}

Cytology

Description

UAS regulatory sequences drive expression of N-terminal Mical sequences.

(Kirilly et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mical

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Mical^N-ter.UAS, Scer\GAL4^ppk.PG is a non-suppressor of abnormal neuroanatomy | pupal stage phenotype of Cul1^GD9650, Scer\GAL4^ppk.PG

(Wong et al., 2013)

Mical^N-ter.UAS, Scer\GAL4^ppk.PG is a non-suppressor of abnormal neuroanatomy | pupal stage phenotype of Scer\GAL4^ppk.PG, SkpA^GD9251

(Wong et al., 2013)

Scer\GAL4^109(2)80/Mical^N-ter.UAS is a non-suppressor of abnormal neuroanatomy phenotype of Sox14^Δ13

(Kirilly et al., 2009)

Mical^N-ter.UAS, Scer\GAL4^109(2)80 is a non-suppressor of abnormal neuroanatomy phenotype of EcR^{B1-ΔC655.W650A.UAS}, Scer\GAL4^109(2)80

(Kirilly et al., 2009)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Mical^N-ter.UAS, Scer\GAL4^ppk.PG is a non-suppressor of larval dorsal multidendritic neuron ddaC | pupal stage phenotype of Cul1^GD9650, Scer\GAL4^ppk.PG

(Wong et al., 2013)

Mical^N-ter.UAS, Scer\GAL4^ppk.PG is a non-suppressor of larval dorsal multidendritic neuron ddaC | pupal stage phenotype of Scer\GAL4^ppk.PG, SkpA^GD9251

(Wong et al., 2013)

Scer\GAL4^109(2)80/Mical^N-ter.UAS is a non-suppressor of dendrite phenotype of Sox14^Δ13

(Kirilly et al., 2009)

Scer\GAL4^109(2)80/Mical^N-ter.UAS is a non-suppressor of larval dorsal multidendritic neuron ddaC phenotype of Sox14^Δ13

(Kirilly et al., 2009)

Mical^N-ter.UAS, Scer\GAL4^109(2)80 is a non-suppressor of dendrite phenotype of EcR^{B1-ΔC655.W650A.UAS}, Scer\GAL4^109(2)80

(Kirilly et al., 2009)

Mical^N-ter.UAS, Scer\GAL4^109(2)80 is a non-suppressor of larval dorsal multidendritic neuron ddaC phenotype of EcR^{B1-ΔC655.W650A.UAS}, Scer\GAL4^109(2)80

(Kirilly et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Mical^{N-ter.Scer\UAS} does not suppress the dendrite pruning defects seen in ddaC neurons expressing lin19^GD9650 under the control of Scer\GAL4^ppk.PG at 16 hours after pupariation.

Expression of Mical^{N-ter.Scer\UAS} does not suppress the dendrite pruning defects seen in ddaC neurons expressing skpA^GD9251 under the control of Scer\GAL4^ppk.PG at 16 hours after pupariation.

(Wong et al., 2013)

Co-expression of Mical^{N-ter.Scer\UAS} with EcR^{B1-ΔC655.W650A.Scer\UAS} in ddaC neurons under the control of Scer\GAL4^109(2)80 fails to affect the excess dendritic arborization found upon expression of EcR^{B1-ΔC655.W650A.Scer\UAS} alone in ddaC neurons under the control of Scer\GAL4^109(2)80.

Expression of Mical^{N-ter.Scer\UAS} in ddaC neurons under the control of Scer\GAL4^109(2)80 in a Sox14^Δ13 homozygous background fails to affect the excess dendritic arborization found in Sox14^Δ13 mutants.

(Kirilly et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to rescue

Mical^N-ter.UAS/Scer\GAL4^ppk.1.9 fails to rescue Mical¹⁵²⁵⁶

(Kirilly et al., 2009)

Mical^N-ter.UAS/Scer\GAL4^ppk.1.9 fails to rescue Mical¹⁵²⁵⁶/Df(3R)swp2^MICAL

(Kirilly et al., 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Mical^{N-ter.Scer\UAS}

Mical^N-ter.UAS

Name Synonyms

Secondary FlyBase IDs

References (13)

Report Sections

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