FlyBase Allele Report: Dmel\ham[UAS.cMa]

Expression of ham^UAS.cMa under the control of Scer\GAL4^wor.PA (in combination with Scer\GAL80^ase.PN to restrict the expression to type II neuroblasts) leads to premature differentiation of type II neuroblasts in larval brains.

(Rives-Quinto et al., 2020)

Expression of ham^Scer\UAS.cMa under the control of Scer\GAL4^pnt-14-94 (limited to a 24 hour period using Scer\GAL80^ts.αTub84B) results in type II neuroblasts with a reduced diameter. A number of cells begin upregulating ase and downregulating the Scer\GAL4 driver, indicating a loss of type II neuroblast identity.

Expression of ham^Scer\UAS.cMa in type I neuroblasts under the control of Scer\GAL4^ase.neuro (limited to a 48 hour period using Scer\GAL80^ts.αTub84B) results in 80% neuroblast loss, and the remaining neuroblasts have fewer progeny, are smaller and often show nuclear pros expression.

(Eroglu et al., 2014)

Expressing ham^UAS.cMa under the control of Scer\GAL4^sca-109-68 results in disrupted notal microchaeta, with either a tormogen (socket) cell partially converted into an ectopic hair-like structure or two complete trichogen (hair) cells and no tormogen cell.

(Endo et al., 2011)

Expression of ham^Scer\UAS.cMa under the control of Scer\GAL4^{neur-GAL4-A101} results in a "balding" of the adult notum.

(Andrews et al., 2009)

Expression of ham^Scer\UAS.cMa under the control of Scer\GAL4^sca-109-68 in all cells of the external sensory organ lineage leads to the loss of both the external cell branch-derived trichogen and tormogen. Expression of ham^Scer\UAS.cMa under the control of Scer\GAL4^{neur-GAL4-A101} in clones in the notum results in the loss of external cells in almost 100% of external sensory organs in the clone.

(Moore et al., 2004)

Expression of ham^Scer\UAS.cMa under the control of Scer\GAL4^pros.PMG results in transformation of multidendritic neurons to external sensory neurons. When ham^Scer\UAS.cMa is expressed under the control of Scer\GAL4^elav.PLu or Scer\GAL4^109(2)80 the branching morphology of the arbors of the multidendritic neurons is substantially reduced, but not eliminated.

(Moore et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^sca-109-68, ham^UAS.cMa has visible | adult stage phenotype, enhanceable by N^264-40/N[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has visible | adult stage phenotype, enhanceable by Su(H)[+]/Su(H)²

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has visible | adult stage phenotype, enhanceable by Su(H)⁸/Su(H)[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has visible | adult stage phenotype, enhanceable by N[+]/N^55e11

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has visible | adult stage phenotype, enhanceable by N¹/N[+]

(Endo et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^sca-109-68, ham^UAS.cMa has visible | adult stage phenotype, suppressible by CtBP[+]/CtBP^87De-10

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has visible | adult stage phenotype, suppressible by CtBP[+]/CtBP⁰³⁴⁶³

(Endo et al., 2011)

Suppressor of

Statement

Reference

Scer\GAL4^erm.PU/ham^UAS.cMa is a suppressor of increased cell number | larval stage phenotype of Df(2L)erm²/erm¹

(Rives-Quinto et al., 2020)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^sca-109-68, ham^UAS.cMa has notal microchaeta | adult stage phenotype, enhanceable by N[+]/N^55e11

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has tormogen cell | adult stage phenotype, enhanceable by N[+]/N^55e11

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has trichogen cell | adult stage | ectopic phenotype, enhanceable by N^264-40/N[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has notal microchaeta | adult stage phenotype, enhanceable by Su(H)[+]/Su(H)²

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has tormogen cell | adult stage phenotype, enhanceable by Su(H)[+]/Su(H)²

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has trichogen cell | adult stage | ectopic phenotype, enhanceable by Su(H)[+]/Su(H)²

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has notal microchaeta | adult stage phenotype, enhanceable by Su(H)⁸/Su(H)[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has tormogen cell | adult stage phenotype, enhanceable by Su(H)⁸/Su(H)[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has trichogen cell | adult stage | ectopic phenotype, enhanceable by Su(H)⁸/Su(H)[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has trichogen cell | adult stage | ectopic phenotype, enhanceable by N[+]/N^55e11

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has notal microchaeta | adult stage phenotype, enhanceable by N¹/N[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has tormogen cell | adult stage phenotype, enhanceable by N¹/N[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has trichogen cell | adult stage | ectopic phenotype, enhanceable by N¹/N[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has notal microchaeta | adult stage phenotype, enhanceable by N^264-40/N[+]

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has tormogen cell | adult stage phenotype, enhanceable by N^264-40/N[+]

(Endo et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^sca-109-68, ham^UAS.cMa has notal microchaeta | adult stage phenotype, suppressible by CtBP[+]/CtBP^87De-10

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has notal microchaeta | adult stage phenotype, suppressible by CtBP[+]/CtBP⁰³⁴⁶³

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has tormogen cell | adult stage phenotype, suppressible by CtBP[+]/CtBP^87De-10

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has tormogen cell | adult stage phenotype, suppressible by CtBP[+]/CtBP⁰³⁴⁶³

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has trichogen cell | ectopic | adult stage phenotype, suppressible by CtBP[+]/CtBP^87De-10

(Endo et al., 2011)

Scer\GAL4^sca-109-68, ham^UAS.cMa has trichogen cell | ectopic | adult stage phenotype, suppressible by CtBP[+]/CtBP⁰³⁴⁶³

(Endo et al., 2011)

Suppressor of

Statement

Reference

Scer\GAL4^erm.PU/ham^UAS.cMa is a suppressor of type II neuroblast | increased number | larval stage phenotype of Df(2L)erm²/erm¹

(Rives-Quinto et al., 2020)

Scer\GAL4^erm.PU/ham^UAS.cMa is a suppressor of embryonic/larval brain | larval stage phenotype of Df(2L)erm²/erm¹

(Rives-Quinto et al., 2020)

Scer\GAL4^{neur-GAL4-A101}/ham^UAS.cMa is a suppressor of tormogen cell | somatic clone phenotype of seq^U5

(Andrews et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of ham^Scer\UAS.cMa under the control of Scer\GAL4^{neur-GAL4-A101} suppresses the gain of socket cells on the adult cuticle that is seen in seq^U5 clones.

(Andrews et al., 2009)

Expression of both sv^Scer\UAS.cKa and ham^Scer\UAS.cMa under the control of Scer\GAL4^{neur-GAL4-A101} in clones in the notum results in the loss of external cells in almost 100% of external sensory organs in the clone.

(Moore et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^erm.PU/ham^UAS.cMa rescues Df(2L)Exel7071/ham^SK1

(Rives-Quinto et al., 2020)

Comments

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Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ham^Scer\UAS.cMa

ham^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Moore

(Moore et al., 2002)

Secondary FlyBase IDs

References (7)

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