FB2024_03 , released June 25, 2024
Allele: Dmel\abUAS.cBa
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General Information
Symbol
Dmel\abUAS.cBa
Species
D. melanogaster
Name
UAS construct of Biehs
FlyBase ID
FBal0181023
Feature type
allele
Associated gene
Dmel\ab
Associated Insertion(s)
Carried in Construct
P{UAS-ab.B}
Also Known As
UAS-ab
Key Links
Transgenic product class
cDNA
(Cook et al., 2004)
wild_type
(Cook et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Cook et al., 2004)
wild_type
(Cook et al., 2004)
Mutagen
in vitro construct
(Cook et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-ab.B}
Cytology
Description

Expression of ab cDNA is under the control of UAS sequences.

(Cook et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
ab
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of abScer\UAS.cBa under the control of Scer\GAL4let-7-C results in diminutive mushroom body α/β lobes.

      (Kucherenko et al., 2012)

      Expression of abScer\UAS.cBa under the control of Scer\GAL4ptc-559.1 in the somatic cells of the germarium (using the temperature sensitive Scer\GAL80ts.αTub84B allele to restrict expression to the adult stage) results in supernumerary germline cells containing a single spectrosome.

      Single cell somatic clones in the ovary expressing abScer\UAS.cBa under the control of Scer\GAL4Act.PU and induced during niche development resemble niche cells by their shape and their ability to anchor germline cells containing a single spectrosome (SSCs). The mutant germaria contain supernumerary SSCs compared to controls.

      (König et al., 2011)

      Ectopic veins form in a cell-autonomous fashion within small abScer\UAS.cBa; Scer\GAL4Ubx.PdC somatic clones in the wing.

      (Cook et al., 2004)

      Ectopic expression of abScer\UAS.cBa under the control of Scer\GAL4109(2)80 results in a 40% reduction in the number of dendritic ends of all dorsal cluster DA neurons in second instar larvae.

      Expression of abScer\UAS.cBa in ddaC neurons, driven by Scer\GAL4477, leads to a 51% decrease in the dendritic branching of these neurons.

      Expression of abScer\UAS.cBa in ddaE and vpda neurons, driven by Scer\GAL4221, leads to a decrease in dendritic branching in these neurons.

      (Li et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      abScer\UAS.cBa
      abUAS.cBa
      Name Synonyms
      UAS construct of Biehs
      (Cook et al., 2004)
      Secondary FlyBase IDs
        References (6)