FlyBase Allele Report: Dmel\JMJD6[UAS.cKa]

General Information

Symbol

Dmel\JMJD6^UAS.cKa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Krieser

FlyBase ID

FBal0219089

Feature type

allele

Associated gene

Dmel\JMJD6

Associated Insertion(s)

Carried in Construct

P{UAS-JMJD6.K}

Key Links

Transgenic product class

cDNA

(Krieser et al., 2007)

wild_type

(Krieser et al., 2007)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Krieser et al., 2007)

wild_type

(Krieser et al., 2007)

Mutagen

in vitro construct

(Krieser et al., 2007)

Progenitor genotype

Carried in construct

P{UAS-JMJD6.K}

Cytology

Description

UASt regulatory sequences drive expression of a PSR cDNA.

(Krieser et al., 2007)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

JMJD6

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^ap-md544

(Krieser et al., 2007)

visible | male, with Scer\GAL4^Act5C.PU

(Krieser et al., 2007)

visible | male, with Scer\GAL4^Tub.PU

(Krieser et al., 2007)

Phenotype Manifest In

eye disc, with Scer\GAL4^GMR.PF

(Krieser et al., 2007)

male genitalia, with Scer\GAL4^Act5C.PU

(Krieser et al., 2007)

male genitalia, with Scer\GAL4^Tub.PU

(Krieser et al., 2007)

wing, with Scer\GAL4^ap-md544

(Krieser et al., 2007)

Detailed Description

Statement

Reference

Expression of PSR^Scer\UAS.cKa under the control of either Scer\GAL4^Act5C or Scer\GAL4^tub results in males with a rotated genitalia defect.

Expression of PSR^Scer\UAS.cKa under the control of Scer\GAL4^ap-md544 results in wing defects, ranging from a wavy wing (54% penetrance), to a ballooned wing that lacks wing blade fusion (39% penetrance).

Expression of PSR^Scer\UAS.cKa under the control of Scer\GAL4^GMR.PF results in extra interommatidial cells in the pupal eye disc.

(Krieser et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

JMJD6^UAS.cKa, Scer\GAL4^Act5C.PU has visible | male phenotype, suppressible by puc^E69/puc[+]

(Krieser et al., 2007)

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/JMJD6^UAS.cKa is a suppressor of visible phenotype of hid^GMR.PG

(Krieser et al., 2007)

Scer\GAL4^GMR.PF/JMJD6^UAS.cKa is a suppressor of visible phenotype of grim^GMR.PC

(Krieser et al., 2007)

Phenotype Manifest In

Suppressed by

Statement

Reference

JMJD6^UAS.cKa, Scer\GAL4^Act5C.PU has male genitalia phenotype, suppressible by puc^E69/puc[+]

(Krieser et al., 2007)

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/JMJD6^UAS.cKa is a suppressor of eye phenotype of hid^GMR.PG

(Krieser et al., 2007)

Scer\GAL4^GMR.PF/JMJD6^UAS.cKa is a suppressor of eye phenotype of grim^GMR.PC

(Krieser et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of PSR^Scer\UAS.cKa under the control of Scer\GAL4^GMR.PF partially suppresses the small rough eye seen in flies expressing W^GMR.PG.

Co-expression of PSR^Scer\UAS.cKa under the control of Scer\GAL4^GMR.PF suppresses the rough eye phenotype seen in flies expressing grim^GMR.PC.

The genital rotation defect seen in males expressing PSR^Scer\UAS.cKa under the control of either Scer\GAL4^Act5C is suppressed by puc^E69/+.

(Krieser et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

JMJD6^UAS.cKa

PSR^Scer\UAS.cKa

PSR^UAS.cKa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Krieser

Secondary FlyBase IDs

References (1)

Report Sections

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