FB2024_03 , released June 25, 2024
Allele: Dmel\TFAMJF02307
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General Information
Symbol
Dmel\TFAMJF02307
Species
D. melanogaster
Name
FlyBase ID
FBal0220676
Feature type
allele
Associated gene
Dmel\TFAM
Associated Insertion(s)
Carried in Construct
P{TRiP.JF02307}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009.3.31)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009.3.31)
Mutagen
in vitro construct
(Perkins et al., 2009.3.31)
Progenitor genotype
Carried in construct
P{TRiP.JF02307}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.3.31)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF02307
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of TFAMJF02307 under the control of Scer\GAL4tim.PE (in combination with Dicer-2 alone or together either with Scer\GAL80Pdf.PS or with tub-Gal80[ts], to restrict expression to the adult stage) but not Scer\GAL4Pdf.PU (in combination with Dicer-2), leads to a significant reduction in the amplitude of locomotor activity rhythm (circadian rhythm) under constant darkness when compared to control adults.

      Expression of TFAMJF02307 under the control of Scer\GAL4elav-C155 does not lead to any changes in the eye color when compared to controls.

      (Chen et al., 2019)

      Scer\GAL4GMR.PU-mediated expression of TFAMJF02307 does not result in an eye phenotype.

      (Zhang et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      Scer\GAL4GMR.PU, TFAMJF02307, pn2 has eye phenotype

      (Zhang et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4GMR.PU-mediated expression of TFAMJF02307 in a pn2 background leads to severely deformed eyes.

      (Zhang et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      TFAMJF02307
      TfamKD
      (Zhang et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)