FlyBase Allele Report: Dmel\ACC[KK102082]

General Information

Symbol

Dmel\ACC^KK102082

Species

D. melanogaster

Name

FlyBase ID

FBal0231618

Feature type

allele

Associated gene

Dmel\ACC

Associated Insertion(s)

Carried in Construct

P{KK102082}

Also Known As

ACC-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102082}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102082

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval tracheal section | larval stage, with Scer\GAL4^sal.BO

(Wicker-Thomas et al., 2015)

Detailed Description

Statement

Reference

When fed on a low carbohydrate diet (0% sucrose supplement), no developmental delay is observed for Scer\GAL4^Cg.PA ACC^KK102082 (plus Dcr-2^Scer\UAS.cDa) animals. In contrast, when fed a 10% or 20% sucrose supplemented diet, these animals exhibit a 2-8 day delay, respectively.

(Garrido et al., 2015)

Expression of spidey^KK100977 under the control of Scer\GAL4^sal.BO (in combination with a Dicer-2 transgene to enhance RNAi efficiency) results in lethality at the L2/L3 transition, accompanied by tracheal defects.

(Wicker-Thomas et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

ACC^KK102082/Scer\GAL4^hs.PB is a suppressor of increased mortality | adult stage | conditional phenotype of Traf-like^Δ

(Lee et al., 2018)

ACC^KK102082/Scer\GAL4^hs.PB is a suppressor of abnormal immune response | adult stage phenotype of Traf-like^Δ

(Lee et al., 2018)

ACC^KK102082, Scer\GAL4^hs.PB is a suppressor of increased mortality | adult stage | conditional phenotype of Atg1^GD7149, Scer\GAL4^hs.PB

(Lee et al., 2018)

ACC^KK102082, Scer\GAL4^hs.PB is a suppressor of abnormal immune response | adult stage phenotype of Atg1^GD7149, Scer\GAL4^hs.PB

(Lee et al., 2018)

ACC^KK102082, Scer\GAL4^hs.PB is a suppressor of increased mortality | adult stage | conditional phenotype of AMPKα^GD736, Scer\GAL4^hs.PB

(Lee et al., 2018)

ACC^KK102082, Scer\GAL4^hs.PB is a suppressor of abnormal immune response | adult stage phenotype of AMPKα^GD736, Scer\GAL4^hs.PB

(Lee et al., 2018)

ACC^KK102082, Scer\GAL4^hs.PB is a suppressor of increased mortality | adult stage | conditional phenotype of Scer\GAL4^hs.PB, wts^KK101055

(Lee et al., 2018)

ACC^KK102082, Scer\GAL4^hs.PB is a suppressor of abnormal immune response | adult stage phenotype of Scer\GAL4^hs.PB, wts^KK101055

(Lee et al., 2018)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Flies co-expressing GlyS^GD12070 and ACC^KK102082 (plus Dcr-2^Scer\UAS.cDa) in both muscles and fat body (via Scer\GAL4^Cg.PA and Scer\GAL4^Mef2.PU) exhibit a prominent reduction in body weight.

(Garrido et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v108631

P{KK102082}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ACC^KK102082

CG11198^KK102082

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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