FB2024_03 , released June 25, 2024
Allele: Dmel\datiKK104525
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General Information
Symbol
Dmel\datiKK104525
Species
D. melanogaster
Name
FlyBase ID
FBal0233038
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of datiKK104525 under the control of Scer\GAL4Bx-MS1096 has no effect on male wing size or patterning.

Expression of datiKK104525 under the control of Scer\GAL4Bx-MS1096 has no effect on female wing size or patterning.

Scer\GAL4Act.PU-mediated expression of datiKK104525 in the presence of Dcr-2Scer\UAS.cDa at 25[o]C results in few adults that die shortly after eclosion with extreme locomotor abnormalities. At 18[o]C, in the absence of Dcr-2Scer\UAS.cDa, females show defects in locomotion and mating acceptance of males, though they court with males normally.

Scer\GAL4elav.PLu-mediated expression of datiKK104525 results in females showing defects in locomotion and mating acceptance of males, though they court with males normally. In contrast, Scer\GAL4repo-mediated expression of datiKK104525 has no effect.

Scer\GAL4Cha.7.4-mediated, but not Scer\GAL4ple.PF-, Scer\GAL4Ddc.PL- or Scer\GAL4Gad1.PS-mediated expression of datiKK104525 (in the presence of Dcr-2Scer\UAS.cDa) results in females showing defects in mating acceptance of males, though they court with males normally.

Females expressing datiKK104525 via Scer\GAL4Cha.7.4 (in the presence of Dcr-2Scer\UAS.cDa) perform as wild type in 'negative geotaxis' climbing assays.

All mushroom body lobes in Scer\GAL4Cha.7.4 datiKK104525 Dcr-2Scer\UAS.cDa animals are wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
CG2052KK104525
Lin29KK104525
datiKK104525
Name Synonyms
Secondary FlyBase IDs
    References (3)