Lin29
Please see the JBrowse view of Dmel\dati for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.47
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.55
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dati using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
dati is specifically expressed in the CNS in embryos and is expressed in the brain and ventral nerve cord in larvae. It is not detected in other larval tissues (wing, eye, leg, and antennal discs). dati is expressed in a complex pattern that involves a few thousand neurons in the brain; about 2,400 central brian neurons (~6.6% of central brain neurons) express dati.
JBrowse - Visual display of RNA-Seq signals
View Dmel\dati in JBrowse4-0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: CG2052 CG10204
Source for merge of: dati CG2052
FlyBase curator comment: The ‘l(4)102CDd’ locus was associated with 11 alleles through to FB2015_01. It was initially defined as a gene with two alleles, l(4)102CDd[1] and l(4)102CDd[2], that failed to complement each other. FBrf0226419 shows that the only extant allele, l(4)102CDd[2], is really a deletion (‘Df(4)BH’) that deletes/disrupts 10 genes, including ‘dati’. It is not known whether the original l(4)102CDd[1] allele, or other alleles in this lethal complementation group, are single lethals inside ‘Df(4)BH’ or also deletions, or whether these define one or more genes. As of FB2015_02, the ‘l(4)102CDd’ locus has been retained as a separate Gene Report, associated with 10 alleles (#1 and #3-11), while the l(4)102CDd[2] allele is now an allele of ‘dati’ (owing to having a break-point in ‘dati’) that is associated with the deletion ‘Df(4)BH’.
Source for merge of CG2052 CG10204 was a shared cDNA ( date:010720 ).
Source for identity of: Lin29 CG2052
Source for identity of: dati Lin29
Named 'datilografo' ('dati'), which means 'typist' in Portuguese, owing to the tapping of the forelegs of the mutants.
Encoded protein is related to C. elegans LIN-29.