FB2024_03 , released June 25, 2024
Allele: Dmel\taiLXXLL.UAS.GFP,Tag:NLS(Unk)
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General Information
Symbol
Dmel\taiLXXLL.UAS.GFP,Tag:NLS(Unk)
Species
D. melanogaster
Name
FlyBase ID
FBal0239114
Feature type
allele
Associated gene
Dmel\tai
Associated Insertion(s)
Carried in Construct
P{UAS-tai.nls.LXXLL-GFP}
Key Links
Transgenic product class
inframe_deletion
(Jang et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Jang et al., 2009)
Mutagen
in vitro construct
(Jang et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-tai.nls.LXXLL-GFP}
Cytology
Description

UASt regulatory sequences drive expression of the tai LXXLL domain which is tagged at the C-terminal end with GFP. The protein is also tagged with a nuclear localization signal (Tag:NLS(Unk)).

(Jang et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tai
Tagged with
GFP
Tag:NLS(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression via Scer\GAL4wor.PA and Scer\GAL80ase.PN prolongs the lifetime and prevents shrinkage of pupal neuroblasts (NBs).

      (Homem et al., 2014)

      Expression of taiLXXLL.Scer\UAS.T:Avic\GFP,T:Uuuu\nls6 under the control of Scer\GAL4slbo.2.6 impairs border cell migration.

      (Jang et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      taiLXXLL.UAS.GFP,Tag:NLS(Unk)/Scer\GAL4c306 fails to rescue tai61G1

      (Jang et al., 2009)
      Comments

      Expression of taiLXXLL.Scer\UAS.T:Avic\GFP,T:Uuuu\nls6 under the control of Scer\GAL4c306 fails to rescue the border cell migration defect of homozygous tai61G1 border cell clones.

      (Jang et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      taiLXXLL.Scer\UAS.T:Avic\GFP,T:Uuuu\nls-Unk
      taiLXXLL.Scer\UAS.T:Avic\GFP,T:Uuuu\nls6
      taiLXXLL.UAS.GFP,Tag:NLS(Unk)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)