P{PdL}magu is located in the first intron of magu, 4646bp upstream of the translation start site. The 3' end of P{PdL}magu is oriented towards the open reading frame.
maguPdL mutants exhibit a 9.3% increase in median life in males and a 5.3% increase in mean life span in males. In females, a 2.2% increase in median life span and a 5.3% increase in mean life span is found.
The presence of maguPdL increases female fecundity in late adult life (from day 30 to day 40) in the presence of DOX from hatching.
maguPdL mutants, where DOX administration is initiated at age 40 days, exhibit increased female fecundity at late ages at one or more DOX concentrations. The late-age administration of drug had no negative effect on female survival (in fact this was increased in maguPdL mutants).