FB2024_03 , released June 25, 2024
Allele: Dmel\RdlUAS.cLa
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General Information
Symbol
Dmel\RdlUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Liu
FlyBase ID
FBal0243635
Feature type
allele
Associated gene
Dmel\Rdl
Associated Insertion(s)
Carried in Construct
P{UAS-Rdl.L}
Also Known As
UAS-Rdl
Key Links
Transgenic product class
wild_type
(Liu et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Liu et al., 2007)
Mutagen
in vitro construct
(Liu et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Rdl.L}
Cytology
Description

UASt regulatory sequence drives expression of Rdl.

(Liu et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Rdl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing RdlScer\UAS.cLa under the control of Scer\GAL4c747 show poorer learning compared to controls after appetitive olfactory conditioning with 1.0M and 2.0M sucrose presented with a conditioned odor. These flies show normal responses to odors and sucrose, indicating the phenotype is not caused by defective sensation.

      (Liu et al., 2009)

      Overexpression of RdlScer\UAS.cLa with Scer\GAL4P2.4.Pdf causes flies to fall asleep faster, remain asleep longer, and show a decrease in sleep latency than controls in the day and night.

      (Parisky et al., 2008)

      Of seven undriven independent insertions of RdlScer\UAS.cLa, all are male sterile.

      Animals overexpressing RdlScer\UAS.cLa by Scer\GAL4c747 show a 30% reduction in olfactory learning compared to controls. Poor olfactory conditioning is independent of the number of shocks received.

      Flies of the genotype Scer\GAL80ts.αTub84B,Scer\GAL4c747/RdlScer\UAS.cLa show a significantly reduced olfactory conditioning performance when shifted to 32[o]C post-eclosion, compared to controls. This effect was seen as soon as 3-6hrs after temperature shift.

      (Liu et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RdlScer\UAS.cLa
      RdlUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Liu
      Secondary FlyBase IDs
        References (3)