FB2024_03 , released June 25, 2024
Allele: Dmel\dlg1WT.UAS.GFP
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General Information
Symbol
Dmel\dlg1WT.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0247449
Feature type
allele
Associated gene
Dmel\dlg1
Associated Insertion(s)
Carried in Construct
P{UAS-dlg1.WT.GFP}
Key Links
Transgenic product class
cDNA
(Zhang et al., 2007)
wild_type
(Zhang et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Zhang et al., 2007)
wild_type
(Zhang et al., 2007)
Mutagen
in vitro construct
(Zhang et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-dlg1.WT.GFP}
Cytology
Description

UASt regulatory sequences drive expression of the wild-type dlg1 S97 cDNA.

(Zhang et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dlg1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The subsynaptic reticulum is overgrown in the boutons of animals expressing dlg1WT.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Mhc.PW compared to controls.

      (Zhang et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dlg1WT.Scer\UAS.T:Avic\GFP partially suppresses the decrease in the number of boutons at the neuromuscular junction which is seen in animals expressing par-1Scer\UAS.cSa under the control of Scer\GAL4Mhc.PW.

      The electrophysiological defects caused by expression of par-1Scer\UAS.cSa under the control of Scer\GAL4Mhc.PW are suppressed by co-expression of dlg1WT.Scer\UAS.T:Avic\GFP.

      (Zhang et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Mhc.PW/dlg1WT.UAS.GFP rescues dlg17

      (Zhang et al., 2007)
      Comments

      Expression of dlg1WT.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Mhc.PW rescues the decrease in the number of boutons at the neuromuscular junction which is seen in dlg17 homozygotes.

      (Zhang et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dlg1WT.Scer\UAS.T:Avic\GFP
      dlg1WT.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)