UAS regulatory sequences drive expression of a short inverted repeat.
The expression of NHMS00001 under the control of Scer\GAL4wor.PA or Scer\GAL4GMR25B11 results in larval central brain neuroblasts ectopically proliferating (i.e. increased numbers in S-phase), compared to controls. The same is observed in stage 16 and 17 embryos.
Intestinal stem cell (ISC) clones expressing NHMS00001 under the control of Scer\GAL4hs.PU produce both ISC-like and EE-like tumors.
Expression of NHMS00001 under the control of Scer\GAL4esg-NP5130 (restricted to the adult stages using Scer\GAL80ts.αTub84B) results in tumor-like intestinal stem cell accumulation.
NHMS00001, Scer\GAL4wor.PA has increased occurrence of cell division | larval stage phenotype, enhanceable by dapHMS05362, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has increased occurrence of cell division | larval stage phenotype, non-enhanceable by Pi3K92EUAS.Tag:MYC, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has increased occurrence of cell division | larval stage phenotype, non-enhanceable by hpoHMS00006, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has increased occurrence of cell division | larval stage phenotype, non-enhanceable by trblHMS04999, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has increased occurrence of cell division | larval stage phenotype, non-suppressible by Pi3K92EUAS.Tag:MYC, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has increased occurrence of cell division | larval stage phenotype, non-suppressible by hpoHMS00006, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has increased occurrence of cell division | larval stage phenotype, non-suppressible by trblHMS04999, Scer\GAL4wor.PA
Scer\GAL4erm.PU/NHMS00001 is a suppressor | partially of increased cell number | larval stage phenotype of Df(2L)Exel7071/hamSK1
NHMS00001, Scer\GAL4wor.PA has larval neuroblast phenotype, enhanceable by dapHMS05362, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval central brain phenotype, enhanceable by dapHMS05362, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval neuroblast phenotype, non-enhanceable by Pi3K92EUAS.Tag:MYC, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval central brain phenotype, non-enhanceable by Pi3K92EUAS.Tag:MYC, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval neuroblast phenotype, non-enhanceable by hpoHMS00006, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval central brain phenotype, non-enhanceable by hpoHMS00006, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval neuroblast phenotype, non-enhanceable by trblHMS04999, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval central brain phenotype, non-enhanceable by trblHMS04999, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4NP5130 has intestinal stem cell | adult stage phenotype, suppressible by mir-bansponge.UAS.DsRed(Unk), Scer\GAL4NP5130
NHMS00001, Scer\GAL4wor.PA has larval neuroblast phenotype, non-suppressible by Pi3K92EUAS.Tag:MYC, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval central brain phenotype, non-suppressible by Pi3K92EUAS.Tag:MYC, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval neuroblast phenotype, non-suppressible by hpoHMS00006, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval neuroblast phenotype, non-suppressible by trblHMS04999, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval central brain phenotype, non-suppressible by hpoHMS00006, Scer\GAL4wor.PA
NHMS00001, Scer\GAL4wor.PA has larval central brain phenotype, non-suppressible by trblHMS04999, Scer\GAL4wor.PA
Scer\GAL4erm.PU/NHMS00001 is a suppressor | partially of type II neuroblast | increased number | larval stage phenotype of Df(2L)Exel7071/hamSK1
Scer\GAL4erm.PU/NHMS00001 is a suppressor | partially of embryonic/larval brain | larval stage phenotype of Df(2L)Exel7071/hamSK1
Expression of bansponge.Scer\UAS.T:Disc\RFP does not suppress the tumor-like intestinal stem cell accumulation seen when NHMS00001 is expressed under the control of Scer\GAL4esg-NP5130 (restricted to the adult stages using Scer\GAL80ts.αTub84B).