The expression of CycE^HMS00060 under the control of Scer\GAL4^A58 leads to the larval epidermis presenting small nuclei, as compared to controls; there are no apparent defects in wound closure.

The expression of CycE^HMS00060 under the control of Scer\GAL4^moody.PU results in a compromised blood-brain barrier in the adult, as dye injected into the body cavity is able to diffuse into the brain. Only at higher expression conditions (i.e. at 25[o]C but not at 18[o]C), larvae show the same blood-brain barrier defects, their brains are significantly smaller and their subperineurial glial cells present septate junction discontinuity (Dlg immunostaining), as well as significant decreases in nuclear size or ploidy.

CycE^HMS00060, Scer\GAL4^esg.PU is a suppressor | partially of adult midgut phenotype of EMC3^GD1074, Scer\GAL4^esg.PU

Scer\GAL4^moody.PU/CycE^HMS00060 is a suppressor | partially of perineurium | adult stage phenotype of mir-285^KO.w-

Scer\GAL4^moody.PU/CycE^HMS00060 is a suppressor | partially of embryonic/larval CNS subperineurial glial cell | larval stage phenotype of mir-285^KO.w-

Scer\GAL4^moody.PU/CycE^HMS00060 is a suppressor | partially of septate junction | larval stage phenotype of mir-285^KO.w-

Scer\GAL4^moody.PU/CycE^HMS00060 is a suppressor of embryonic/larval brain | larval stage phenotype of mir-285^KO.w-

Scer\GAL4^moody.PU/CycE^HMS00060 is a suppressor of nucleus | larval stage phenotype of mir-285^KO.w-