FB2024_03 , released June 25, 2024
Allele: Dmel\parkT187A.UAS.Tag:MYC
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General Information
Symbol
Dmel\parkT187A.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0258535
Feature type
allele
Associated gene
Dmel\park
Associated Insertion(s)
Carried in Construct
P{UAS-park.MYC.T187A}
Key Links
Transgenic product class
missense_variant
(Kim et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Kim et al., 2008)
Mutagen
in vitro construct
(Kim et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-park.MYC.T187A}
Cytology
Description

UAS regulatory sequences drive expression of a T187A mutant of park tagged with Tag:MYC.

(Kim et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
park
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      parkT187A.UAS.Tag:MYC/Scer\GAL4hs.PB is a suppressor | partially of mitochondrion phenotype of Pink1B9, park1

      (Kim et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of parkT187A.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4hs.PB partially suppresses the mitochondrial swelling phenotype in Pink1B9, park1 double mutants.

      (Kim et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      parkT187A.UAS.Tag:MYC partially rescues park1

      (Kim et al., 2008)
      Comments

      The mitochondrial morphology in the indirect flight muscle of park1 mutants is partially rescued by expression of parkT187A.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4hs.PB

      (Kim et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      parkT187A.Scer\UAS.T:Hsap\MYC
      parkT187A.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)