FlyBase Allele Report: Dmel\moody[KK100674]

General Information

Symbol

Dmel\moody^KK100674

Species

D. melanogaster

Name

FlyBase ID

FBal0258794

Feature type

allele

Associated gene

Dmel\moody

Associated Insertion(s)

Carried in Construct

P{KK100674}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK100674}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK100674

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of moody^KK100674 under the control of Scer\GAL4^tey-5053A (in combination with a Dicer-2 transgene to enhance RNAi efficiency) does not cause any difference in growth response of motoneuron axons after nerve crush injury in third instar larvae, as compared to wild type.

(Hao et al., 2016)

Females that express moody^KK100674 in glial cells using Scer\GAL4^repo are viable and behave as wild-type females with regard to mating.

(Haussmann et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

moody^KK100674, Scer\GAL4^tey-5053A is a non-suppressor of abnormal wound healing | third instar larval stage phenotype of Mmus\Prkaca^mC.UAS, Scer\GAL4^tey-5053A

(Hao et al., 2016)

moody^KK100674, Scer\GAL4^tey-5053A is a non-suppressor of increased cell growth rate | third instar larval stage | conditional phenotype of Mmus\Prkaca^mC.UAS, Scer\GAL4^tey-5053A

(Hao et al., 2016)

moody^KK100674/Scer\GAL4^repo is a non-suppressor of abnormal mating behavior | mated female limited phenotype of SP⁰

(Haussmann et al., 2013)

Df(1)JC70, moody^KK100674, Scer\GAL4^repo, Df(1)Exel6234 is a non-suppressor of abnormal mating behavior | mated female limited phenotype of SP⁰

(Haussmann et al., 2013)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

moody^KK100674, Scer\GAL4^tey-5053A is a non-suppressor of axon | third instar larval stage | conditional phenotype of Mmus\Prkaca^mC.UAS, Scer\GAL4^tey-5053A

(Hao et al., 2016)

moody^KK100674, Scer\GAL4^tey-5053A is a non-suppressor of motor neuron | third instar larval stage | conditional phenotype of Mmus\Prkaca^mC.UAS, Scer\GAL4^tey-5053A

(Hao et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Df(1)JC70/Df(1)Exel6234 mutant females expressing Scer\GAL4^repo>moody^KK100674 show post-mating behaviour that is similar to that of wild-type females, i.e. receptivity is reduced and oviposition increased.

Females expressing Scer\GAL4^repo>moody^KK100674 mated with SP⁰ mutant males behave very much like virgins.

Df(1)JC70/Df(1)Exel6234 females expressing Scer\GAL4^repo>moody^KK100674 mated with SP⁰ mutant males behave very much like virgins.

(Haussmann et al., 2013)

Xenogenetic Interactions

Statement

Reference

Co-expression of moody^KK100674 does not suppress the enhanced growth response of motoneuron axons after nerve crush injury seen in larvae expressing Mmus\Pkaca^mC.Scer\UAS under the control of Scer\GAL4^tey-5053A.

(Hao et al., 2016)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v109601

P{KK100674}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

moody^KK100674

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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