FB2024_03 , released June 25, 2024
Allele: Dmel\Usp14KK102888
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General Information
Symbol
Dmel\Usp14KK102888
Species
D. melanogaster
Name
FlyBase ID
FBal0259240
Feature type
allele
Associated gene
Dmel\Usp14
Associated Insertion(s)
Carried in Construct
P{KK102888}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK102888}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK102888
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Usp14KK102888 under the control of Scer\GAL4da.PU leads to third instar larvae showing increased sensitive to UV radiation.

      (Páhi et al., 2022)

      Testes of males expressing Usp14KK102888 under the control of Scer\GAL4VP16.bam, but not Scer\GAL4Act5C.PU, exhibit sperm individualization defects, as compared to controls.

      (Kovács et al., 2020)

      No phenotype is observed when CG5384KK102888 is expressed using Scer\GAL4sqh.PW.

      Scer\GAL4elav.PU, CG5384KK102888 adults are slower than controls and are dead by 40 days.

      (Tsou et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      Usp14KK102888, Scer\GAL4GMR.PFa is a non-enhancer of eye phenotype of DroncUAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Usp14KK102888, Scer\GAL4GMR.PFa is a non-enhancer of eye phenotype of DroncS130A.UAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)
      NOT Suppressor of
      Statement
      Reference

      Usp14KK102888, Scer\GAL4GMR.PFa is a non-suppressor of eye phenotype of DroncUAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Usp14KK102888, Scer\GAL4GMR.PFa is a non-suppressor of eye phenotype of DroncS130A.UAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The photoreceptor depigmentation phenotype characteristic for adult flies expressing either DroncUAS.cSa or DroncS130A.UAS.cSa under the control of Scer\GAL4GMR.PFa is not significantly modified by the co-expression of Usp14KK102888.

      (Sinenko, 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG5384KK102888
      Usp14KK102888
      (Kovács et al., 2020)
      Usp14RNAi
      (Kovács et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)