FB2024_03 , released June 25, 2024
Allele: Dmel\pntUAS.P1.cZa
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General Information
Symbol
Dmel\pntUAS.P1.cZa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Zhu
FlyBase ID
FBal0268493
Feature type
allele
Associated gene
Dmel\pnt
Associated Insertion(s)
Carried in Construct
P{UAS-pnt.P1.Z}
Also Known As
UAS-PntP1
Key Links
Transgenic product class
wild_type
(Zhu et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Zhu et al., 2011)
Mutagen
in vitro construct
(Zhu et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-pnt.P1.Z}
Cytology
Description

UAS regulatory sequences drive expression of the pntP1 isoform.

(Zhu et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
pnt
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of pntUAS.P1.cZa under the control of Scer\GAL4insc-Mz1407 results in ectopic mature intermediate neural progenitor-like cells in type I neuroblast lineages in the larval ventral nerve cord.

      (Chen et al., 2021)

      Expression of pntScer\UAS.P1.cZa in neuroblasts using Scer\GAL4insc-Mz1407 (restricted to the larval stages onwards using Scer\GAL80ts.αTub84B) results in ectopic type II intermediate neural progenitor-like cells in the type I neuroblast lineage of the ventral brain and ventral nerve cord. No overproliferation of the type I neuroblasts is seen.

      Expression of pntScer\UAS.P1.cZa in a type I neuroblast clone under the control of Scer\GAL4insc-Mz1407 and Scer\GAL4elav-C155 induces the generation of multiple mature intermediate neural progenitor-like cells.

      (Zhu et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of aseScer\UAS.cBa largely suppresses the production of ectopic intermediate neural progenitor-like cells seen in the type I neuroblasts of the ventral brain and ventral nerve cord when pntScer\UAS.P1.cZa is expressed under the control of Scer\GAL4insc-Mz1407.

      Co-expression of pntScer\UAS.P1.cZa and bratHM05078 in the type I neuroblasts of the ventral nerve cord using Scer\GAL4insc-Mz1407 results in overproliferation of type II neuroblast-like cells.

      (Zhu et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      pntScer\UAS.P1.cZa
      pntUAS.P1.cZa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Zhu
      Secondary FlyBase IDs
        References (3)