FB2024_03 , released June 25, 2024
Allele: Dmel\Su(H)WARE.UAS
Open Close
General Information
Symbol
Dmel\Su(H)WARE.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0276772
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of Su(H) which contains the amino acid replacements W491A and R493E.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Su(H)WARE.Scer\UAS in the central domain of the wing disc under the control of Scer\GAL4bi-omb-Gal4 results in hyperproliferation.

Expression of Su(H)WARE.Scer\UAS under the control of Scer\GAL4GMR.PF results in overproliferation of eye tissue.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Su(H)WARE.Scer\UAS enhances the wing disc tissue loss seen when HScer\UAS.attB.cMa is expressed under the control of Scer\GAL4bi-omb-Gal4.

Expression of HLD.Scer\UAS does not suppress the wing disc hyperproliferation phenotype seen when Su(H)WARE.Scer\UAS is expressed under the control of Scer\GAL4bi-omb-Gal4.

Expression of Su(H)WARE.Scer\UAS enhances the eye phenotype seen when HScer\UAS.attB.cMa is expressed under the control of Scer\GAL4GMR.PF. Only small slits lacking ommatidial structures and eye colour remain.

Expression of HLD.Scer\UAS does not suppress the eye hyperproliferation phenotype seen when Su(H)WARE.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Su(H)WARE.Scer\UAS
Su(H)WARE.UAS
Name Synonyms
Secondary FlyBase IDs
    References (1)