FB2024_03 , released June 25, 2024
Allele: Dmel\Tcs5UAS.C.Tag:MYC
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General Information
Symbol
Dmel\Tcs5UAS.C.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0284607
Feature type
allele
Associated gene
Dmel\Tcs5
Associated Insertion(s)
Carried in Construct
P{UAS-Tcs5-myc}
Key Links
Transgenic product class
wild_type
(Ibar et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ibar et al., 2013)
Mutagen
in vitro construct
(Ibar et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-Tcs5-myc}
Cytology
Description

UAS regulatory sequences drive expression of Prpk which is tagged at the C-terminal end with Tag:MYC.

(Ibar et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Tcs5
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of PrpkScer\UAS.C.T:Hsap\MYC under the control of Scer\GAL4da.G32 does not result in a change in larval size compared to controls.

      (Ibar et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Tcs5UAS.C.Tag:MYC/Scer\GAL4da.G32 rescues Tcs5RNAi.UAS.462

      (Ibar et al., 2013)

      Scer\GAL4salm.EPv/Tcs5UAS.C.Tag:MYC rescues Tcs5RNAi.UAS.462

      (Ibar et al., 2013)

      Scer\GAL4Act5C.PU/Tcs5UAS.C.Tag:MYC rescues Tcs5RNAi.UAS.462

      (Ibar et al., 2013)
      Comments

      Co-expression of PrpkScer\UAS.C.T:Hsap\MYC rescues the reduction in larval size caused by expression of PrpkdsRNA.Scer\UAS.462 under the control of Scer\GAL4da.G32.

      Co-expression of PrpkScer\UAS.C.T:Hsap\MYC rescues the reduction in distance between wing veins 3 and 4 caused by expression of PrpkdsRNA.Scer\UAS.462 under the control of Scer\GAL4salm.EPv.

      Co-expression of PrpkScer\UAS.C.T:Hsap\MYC rescues the small and apoptotic nature of clones in the third larval instar wing disc expressing PrpkdsRNA.Scer\UAS.462 under the control of Scer\GAL4Act5C.PU (clones induced at 60 +/- 12 hours after egg laying).

      Co-expression of PrpkScer\UAS.C.T:Hsap\MYC rescues the small size of clones in the third larval instar fat body expressing PrpkdsRNA.Scer\UAS.462 under the control of Scer\GAL4Act5C.PU (clones induced 36 +/- 12 hours after egg laying).

      (Ibar et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      PrpkScer\UAS.C.T:Hsap\MYC
      PrpkUAS.C.Tag:MYC
      Tcs5UAS.C.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)