FlyBase Allele Report: Dmel\tal[UAS.cPa]

General Information

Symbol

Dmel\tal^UAS.cPa

Species

D. melanogaster

Name

FlyBase ID

FBal0285352

Feature type

allele

Associated gene

tal

Associated Insertion(s)

Carried in Construct

P{UAS-tal.P}

Key Links

Transgenic product class

wild_type

(Pi et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Pi et al., 2011)

Mutagen

in vitro construct

(Pi et al., 2011)

Progenitor genotype

Carried in construct

P{UAS-tal.P}

Cytology

Description

UAS regulatory sequences drive expression of full-length tal coding sequences.

(Pi et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

tal

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

external sensory organ | ectopic, with Scer\GAL4^dpp.blk1

(Pi et al., 2011)

mesothoracic tergum, with Scer\GAL4^dpp.blk1

(Pi et al., 2011)

Detailed Description

Statement

Reference

Expression of tal^Scer\UAS.cPa under the control of Scer\GAL4^dpp.blk1 induces a few ectopic external sensory organs, compared to controls.

In pupae expressing tal^Scer\UAS.cPa under the control of Scer\GAL4^dpp.blk1 exhibit more than four peb-positive clusters, indicating the formation of ectopic sensory organ precursors.

Expression of tal^Scer\UAS.cPa in the wing disc, under the control of Scer\GAL4^dpp.blk1, does not affect wing vein formation.

(Pi et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^dpp.blk1, tal^UAS.cPa has external sensory organ | ectopic phenotype, enhanceable by phyl^UAS.cPa/Scer\GAL4^dpp.blk1

(Pi et al., 2011)

Scer\GAL4^dpp.blk1, tal^UAS.cPa has mesothoracic tergum phenotype, enhanceable by phyl^UAS.cPa/Scer\GAL4^dpp.blk1

(Pi et al., 2011)

Scer\GAL4^Eq, tal^UAS.cPa has external sensory organ | ectopic phenotype, enhanceable by phyl^UAS.cPa/Scer\GAL4^Eq

(Pi et al., 2011)

Scer\GAL4^Eq, tal^UAS.cPa has mesothoracic tergum phenotype, enhanceable by phyl^UAS.cPa/Scer\GAL4^Eq

(Pi et al., 2011)

Enhancer of

Statement

Reference

tal^UAS.cPa/Scer\GAL4^dpp.blk1 is an enhancer of external sensory organ | ectopic phenotype of Scer\GAL4^dpp.blk1, phyl^UAS.cPa

(Pi et al., 2011)

tal^UAS.cPa/Scer\GAL4^dpp.blk1 is an enhancer of mesothoracic tergum phenotype of Scer\GAL4^dpp.blk1, phyl^UAS.cPa

(Pi et al., 2011)

Scer\GAL4^Eq/tal^UAS.cPa is an enhancer of external sensory organ | ectopic phenotype of Scer\GAL4^Eq, phyl^UAS.cPa

(Pi et al., 2011)

Scer\GAL4^Eq/tal^UAS.cPa is an enhancer of mesothoracic tergum phenotype of Scer\GAL4^Eq, phyl^UAS.cPa

(Pi et al., 2011)

tal^UAS.cPa/Scer\GAL4^dpp.blk1 is an enhancer of wing vein L3 phenotype of N^55e11

(Pi et al., 2011)

tal^UAS.cPa/Scer\GAL4^dpp.blk1 is an enhancer of wing phenotype of N^55e11

(Pi et al., 2011)

Other

Statement

Reference

Scer\GAL4^dpp.blk1, phyl^UAS.cPa, tal^UAS.cPa has wing vein L3 phenotype

(Pi et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of tal^Scer\UAS.cPa and phyl^Scer\UAS.cPa under the control of Scer\GAL4^Eq1 induces ectopic external sensory organs on the notum.

Co-expression of tal^Scer\UAS.cPa and phyl^Scer\UAS.cPa under the control of Scer\GAL4^dpp.blk1 induces approximately 7.4 (+/- 1.5) ectopic external sensory organs.

Co-expression of tal^Scer\UAS.cPa and phyl^Scer\UAS.cPa in the wing disc under the control of Scer\GAL4^dpp.blk1 causes strong L3 vein expansion that is accompanied by ectopic external sensory organ formation.

Expression of tal^Scer\UAS.cPa by Scer\GAL4^dpp.blk1 in N^55e11 heterozygotes strongly enhances the expansion of L3 veins with complete penetrance.

Expression of tal^Scer\UAS.cPa by Scer\GAL4^dpp.blk1 enhances the wing-notching phenotype found in N^55e11 heterozygotes.

(Pi et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

tal^Scer\UAS.cPa

tal^UAS.cPa

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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