FB2024_03 , released June 25, 2024
Allele: Dmel\jumuHp126
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General Information
Symbol
Dmel\jumuHp126
Species
D. melanogaster
Name
FlyBase ID
FBal0286392
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Imprecise excision of P{PZ}jumu06439 results in the 5' portion of the P{PZ} insertion remaining in jumu intron 1.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Approximately two-thirds of jumuHp126 homozygotes die as pharate adults. The remainder exhibit rough eyes and notched wings. The formation of longitudinal vein 5 is also incomplete in these escapers and bristles on the notum are occasionally lost. These phenotypes are more severe in jumuHp126/jumu06439 heterozygotes. Sections of mutant eyes reveal an irregular array of ommatidia, and the inner R7 and, to a lesser extent, out photoreceptor cells are missing in a considerable fraction of ommatidia. The spacing of presumptive photoreceptor cell clusters are irregular in mutant eye imaginal discs, with some clusters fused. In this region of the mutant disc, a great increase in dead cells is observed/ F-actin is also found to have accumulated in the cells anterior to the morphogenetic furrow.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)