FB2024_03 , released June 25, 2024
Allele: Dmel\osk+tMa
Open Close
General Information
Symbol
Dmel\osk+tMa
Species
D. melanogaster
Name
FlyBase ID
FBal0298349
Feature type
allele
Associated gene
Dmel\osk
Associated Insertion(s)
Carried in Construct
P{oskWT}
Key Links
Transgenic product class
genomic_DNA
(Morais-de-Sá et al., 2013)
wild_type
(Morais-de-Sá et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Morais-de-Sá et al., 2013)
wild_type
(Morais-de-Sá et al., 2013)
Mutagen
phiC31 integrase
(Morais-de-Sá et al., 2013)
in vitro construct
(Morais-de-Sá et al., 2013)
Progenitor genotype
Carried in construct
P{oskWT}
Cytology
Description

Genomic fragment containing wild-type osk.

(Morais-de-Sá et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
osk
Encoded product / tool
osk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of oskt.WT in osk1/Df(3R)p-XT103 mutant mothers results in embryos containing an average of 24 pole cells, as in wild-type.

      One copy of oskt.WT suppresses the arrest in oogenesis found in oskA87/Df(3R)p-XT103. However, 10% of the resulting embryos are missing abdominal segments, displaying a weak posterior group phenotype.

      (Morais-de-Sá et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Embryos derived from mago1/Df(3R)p-XT103 mutants exhibit abdominal and head defects (in up to 35% of embryos). The presence of one copy of oskt.WT partially suppresses these defects.

      (Morais-de-Sá et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      osk+tMa rescues osk1/Df(3R)p-XT103

      (Morais-de-Sá et al., 2013)
      Comments

      Expression of oskt.WT in osk1/Df(3R)p-XT103 mutant mothers results in embryos containing an average of 24 pole cells, as in wild-type.

      (Morais-de-Sá et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      osk+tMa
      oskt.WT
      Name Synonyms
      Secondary FlyBase IDs
        References (1)