Amino acid replacement: ?857term.
C23854752A
C857term | bgcn-PA; C852term | bgcn-PB
?857term
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. Mutation reported as a premature stop codon after residue 857. The mutation was mapped relative to isoform bgcn-PA, the only annotated form at the time of publication.
Mutant germaria are tumorous, containing only undifferentiated germline stem cell-like single germ cells.
bgcn20915 germline stem cell (GSC) clones outcompete normal, wild type GSCs and occupy their niches within germaria. This appears to happen by the mutant GSCs simply forcing out the neighbouring wild type GSCs, as neither apoptosis nor differentiation is induced.
bgcn20915 germline stem cells (GSCs) divide at a similar rate to controls.
bgcn20915 has female germline stem cell | germline clone phenotype, non-suppressible by shg10469