FB2024_03 , released June 25, 2024
Allele: FHV\B2UASp.Tag:FLAG
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General Information
Symbol
FHV\B2UASp.Tag:FLAG
Species
A. Flock House virus
Name
FlyBase ID
FBal0314171
Feature type
allele
Associated gene
FHV\B2
Associated Insertion(s)
Carried in Construct
P{UASp-B2.FLAG}
Transgenic product class
wild_type
(Berry et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Berry et al., 2009)
Mutagen
in vitro construct
(Berry et al., 2009)
Progenitor genotype
Carried in construct
P{UASp-B2.FLAG}
Cytology
Description

UASp regulatory sequences drive expression of Tag:FLAG-tagged FHV\B2.

(Berry et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
FHV\B2
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  viral infectious disease
      CEA with FHV\B2RNA1Δ.UAS
      (Berry et al., 2009)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Upon infection with Drosophila C virus (DCV), 50% of wild-type flies die within 6 to 7 days. Flies expressing FHV\B2Scer\UAS.P\T.T:Zzzz\FLAG under the control of the ubiquitous Scer\GAL4Act5C.PU driver show a more rapid course of disease and die faster after inoculation with DCV. Similar results are obtained when the transgene is expressed under the control of Scer\GAL4hs.PB after heat-shock induction.

      (Berry et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4GMR.PF/FHV\B2UASp.Tag:FLAG is a suppressor of visible phenotype of wRNAi.GMR

      (Berry et al., 2009)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4GMR.PF/FHV\B2UASp.Tag:FLAG is a suppressor of eye phenotype of wRNAi.GMR

      (Berry et al., 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      FHV\B2Scer\UAS.P\T.T:Zzzz\FLAG
      FHV\B2UASp.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)