FB2024_03 , released June 25, 2024
Allele: Dmel\galla-2Δ203
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General Information
Symbol
Dmel\galla-2Δ203
Species
D. melanogaster
Name
FlyBase ID
FBal0317015
Feature type
allele
Associated gene
Dmel\galla-2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Yeom et al., 2015)
Progenitor genotype
P{EP}G5485
(Yeom et al., 2015)
Cytology
Description

Imprecise excision of P{EP}G5485 has resulted in a deletion that removes the entire 526bp galla-2 coding sequence.

(Yeom et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:10,882,890..10,883,705 [+]
Comment:

Inferred boundaries of an 816 bp deletion resulting from the imprecise excision of P{EP}G5485 that extends downstream from the P element insertion site and removes all of galla-2.

(Yeom et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      galla-2Δ203/galla-2[+] is an enhancer of partially lethal - majority die phenotype of galla-1Δ182

      (Yeom et al., 2015)
      Suppressor of
      Statement
      Reference

      galla-2Δ203/galla-2[+] is a suppressor | partially of visible phenotype of Scer\GAL4GMR.PU, crbintra.UAS.Tag:MYC

      (Yeom et al., 2015)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      galla-2Δ203/galla-2[+] is a suppressor | partially of eye phenotype of Scer\GAL4GMR.PU, crbintra.UAS.Tag:MYC

      (Yeom et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of galla-2Δ203 considerably suppresses the small and rough eye phenotype seen when crbintra.Scer\UAS.T:Hsap\MYC is expressed under the control of Scer\GAL4GMR.PU.

      galla-2Δ203 mutant embryos show chromosome segregation defect phenotypes such as chromosome bridges and chromosome-free centrosomes.

      The partial lethality seen in galla-1Δ182 mutants is considerably enhanced by one copy of galla-2Δ203.

      (Yeom et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      galla-2Δ203
      Name Synonyms
      Secondary FlyBase IDs
        References (1)