FB2024_03 , released June 25, 2024
Allele: Dmel\MgtorUAS.cLa
Open Close
General Information
Symbol
Dmel\MgtorUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Liu
FlyBase ID
FBal0324942
Feature type
allele
Associated gene
Dmel\Mgtor
Associated Insertion(s)
Carried in Construct
P{UAS-Mgtor.L}
Key Links
Transgenic product class
cDNA
(Liu et al., 2015)
wild_type
(Liu et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Liu et al., 2015)
wild_type
(Liu et al., 2015)
Mutagen
in vitro construct
(Liu et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Mgtor.L}
Cytology
Description

UASt regulatory sequences drive expression of a full-length Mtor cDNA.

(Liu et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mgtor
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of MtorScer\UAS.cLa alone under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 has no obvious effect on the germline stem cell population in adult testes, as compared to controls.

      (Liu et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4VP16.nanos.UTR/MgtorUAS.cLa rescues MgtorGD13871

      (Liu et al., 2015)

      Scer\GAL4VP16.nanos.UTR/MgtorUAS.cLa rescues Mgtork03905

      (Liu et al., 2015)
      Comments

      Co-expression of MtorScer\UAS.cLa under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 rescues the germline stem cell number defects present in the testis of adults expressing MtorGD13871 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16; this expression also rescues the germline stem cell loss seen in Mtork03905 homozygous germline clones.

      (Liu et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      MgtorUAS.cLa
      MtorScer\UAS.cLa
      MtorUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Liu
      Secondary FlyBase IDs
        References (1)