FB2024_03 , released June 25, 2024
Allele: Dmel\rheaΔ486-1937.GFP
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General Information
Symbol
Dmel\rheaΔ486-1937.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0325471
Feature type
allele
Associated gene
Dmel\rhea
Associated Insertion(s)
Carried in Construct
P{GFP-talin.Δ486-1937}
Key Links
Transgenic product class
inframe_deletion
(Maartens et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Maartens et al., 2016)
Mutagen
in vitro construct
(Maartens et al., 2016)
Progenitor genotype
Carried in construct
P{GFP-talin.Δ486-1937}
Cytology
Description

Encodes rhea lacking a portion of the rod domain (amino acid residues 486-1937 are deleted). It retains 3 C-terminal Vinc protein-binding sites and the dimerization helix. The protein is tagged at the N-terminal end with GFP.

(Maartens et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
rhea
Encoded product / tool
rhea
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The expression of rheaΔ486-1937.T:Avic\GFP in Df(3L)79a homozygous follicle cell clones leads to a strong reduction in the number of ectopic VincCO.Scer\UAS.P\T.T:Equa\eqFP578-TagRFP-positive cytoplasmic protein aggregates observed upon Scer\GAL4Act5C.PU-driven expression in those clones.

      (Maartens et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      rheaΔ486-1937.GFP
      rheaΔ486-1937.T:Avic\GFP
      talinΔ486-1937
      (Maartens et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)