Expressing Adck1UAS.cYa under the control of Scer\GAL4Sgs3.PD results in mitochondria with a smaller area than controls in salivary glands of third instar larvae.
Expressing Adck1UAS.cYa under the control of Scer\GAL4Mhc.PU results in abnormal thoracic muscle structure and mitochondria with severely destroyed cristae in adults. Flies show reduced locomotor activity and slower walking speed than controls.
Adck1UAS.cYa, Scer\GAL4Mef2.PU has lethal - all die before end of P-stage phenotype, suppressible by YME1LGD2166, Scer\GAL4Mef2.PU
Adck1UAS.cYa, Scer\GAL4Mef2.PU has lethal - all die before end of P-stage phenotype, suppressible by MitofilinUAS.cYa, Scer\GAL4Mef2.PU
Adck1UAS.cYa, Scer\GAL4Mef2.PU has lethal - all die before end of P-stage phenotype, suppressible by Opa1UAS.cYa, Scer\GAL4Mef2.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by YME1LGD2166, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by MitofilinUAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by Opa1UAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU is an enhancer of abnormal locomotor behavior | adult stage phenotype of MitofilinUAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU is a non-enhancer of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4Mhc.PU, YME1LGD2166
Adck1UAS.cYa, Scer\GAL4Mhc.PU is a non-enhancer of abnormal locomotor behavior | adult stage phenotype of Opa1UAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU is a non-suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4Mhc.PU, YME1LGD2166
Adck1UAS.cYa, Scer\GAL4Mhc.PU is a non-suppressor of abnormal locomotor behavior | adult stage phenotype of Opa1UAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has adult somatic muscle cell of thorax phenotype, suppressible | partially by Opa1UAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has mitochondrion | adult stage phenotype, suppressible | partially by YME1LGD2166, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has mitochondrion | adult stage phenotype, suppressible | partially by MitofilinUAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has mitochondrion | adult stage phenotype, suppressible | partially by Opa1UAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has adult somatic muscle cell of thorax phenotype, suppressible | partially by YME1LGD2166, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU has adult somatic muscle cell of thorax phenotype, suppressible | partially by MitofilinUAS.cYa, Scer\GAL4Mhc.PU
Adck1UAS.cYa, Scer\GAL4Mhc.PU is a suppressor | partially of adult somatic muscle cell of thorax phenotype of Scer\GAL4Mhc.PU, YME1LGD2166
Adck1UAS.cYa, Scer\GAL4Mhc.PU is a suppressor | partially of mitochondrion | adult stage phenotype of Scer\GAL4Mhc.PU, YME1LGD2166
Adck1UAS.cYa, MitofilinUAS.cYa, Scer\GAL4Mhc.PU has mitochondrion | adult stage phenotype
Adck1UAS.cYa, Opa1UAS.cYa, Scer\GAL4Mhc.PU has adult somatic muscle cell of thorax phenotype
Adck1UAS.cYa, Opa1UAS.cYa, Scer\GAL4Mhc.PU has mitochondrion | adult stage phenotype
Adult flies co-expressing Adck1UAS.cYa and either MitofilinUAS.cYa or Opa1UAS.cYa under the control of Scer\GAL4Mhc.PU display unusual elongated and continuous mitochondria in thoracic muscles.
Scer\GAL4Mef2.PU/Adck1UAS.cYa partially rescues Adck1del
Expressing Adck1UAS.cYa under the control of Scer\GAL4hs.PB in Adck1del/Adck1del animals fully rescues developmental rate defects and flies progress normally into the adult stage. When expression is under the control of Scer\GAL4Mef2.PU, developmental rate is only partially rescued and larvae develop into the third instar stage.