FB2024_03 , released June 25, 2024
Allele: Dmel\Top2UAS.cYa
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General Information
Symbol
Dmel\Top2UAS.cYa
Species
D. melanogaster
Name
UAS construct a of Yang
FlyBase ID
FBal0369957
Feature type
allele
Associated gene
Dmel\Top2
Associated Insertion(s)
Carried in Construct
PBac{UAS-Top2.Y}
Key Links
Transgenic product class
cDNA
(Yang et al., 2021)
wild_type
(Yang et al., 2021)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yang et al., 2021)
wild_type
(Yang et al., 2021)
Mutagen
in vitro construct
(Yang et al., 2021)
Progenitor genotype
Carried in construct
PBac{UAS-Top2.Y}
Cytology
Description

UASt regulatory sequences drive expression of Top2 cDNA (DGRC RE49802 with correction of mutations).

(Yang et al., 2021)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Top2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Top2UAS.cYa under the control of Scer\GAL4ey.PU results in small eyes. The expression of Top2UAS.cYa under the control of Scer\GAL4en.PU induces a small wing, The expression of Top2UAS.cYa under the control of Scer\GAL4en.PU or Scer\GAL4nub.PU induces a small, wrinkled wing,

      (Yang et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4nub.PU/Top2UAS.cYa is a suppressor | partially of wing phenotype of Scer\GAL4nub.PU, TctpRNAi.UAS

      (Yang et al., 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Top2UAS.cYa
      Name Synonyms
      UAS construct a of Yang
      Secondary FlyBase IDs
        References (1)