FB2024_03 , released June 25, 2024
Allele: Dmel\IntS8SH1314
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General Information
Symbol
Dmel\IntS8SH1314
Species
D. melanogaster
Name
FlyBase ID
FBal0388546
Feature type
allele
Associated gene
Dmel\IntS8
Associated Insertion(s)
P{lacW}IntS8SH1314
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Oh et al., 2003)
Progenitor genotype
Associated Insertion(s)
P{lacW}IntS8SH1314
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      IntS8SH1314 type II neuroblast clones in the larval brain contain many supernumerary neuroblast-like cells and significantly fewer intermediate neural progenitor-like cells (both immature Dpn-negative, PntP1-positive INPs or mature Dpn-positive, Ase-positive INPs), as compared to controls.

      (Zhang et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      The lethality of the original insertion chromosome may or may not be caused by this allele.

      (FlyBase Curators, 2008-)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CG5859SH1314
      IntS8SH1314
      (Liu et al., 2023)
      intS8SH1314
      (Zhang et al., 2019)
      l(2)SH1314SH1314
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0242903
      • FBal0143711
      References (5)