FB2024_03 , released June 25, 2024
Allele: Dmel\bunA.UAS
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General Information
Symbol
Dmel\bunA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0402479
Feature type
allele
Associated gene
Dmel\bun
Associated Insertion(s)
Carried in Construct
P{UAS-bun.A}
Also Known As
UAS-BunA
Key Links
Transgenic product class
wild_type
(Gluderer et al., 2008, Dobens et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Gluderer et al., 2008, Dobens et al., 2000)
Mutagen
in vitro construct
(Gluderer et al., 2008, Dobens et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-bun.A}
Cytology
Description

UAS regulatory sequences drive expression of the bun A isoform.

(Gluderer et al., 2008)

UASt regulatory sequences drive expression of the bun-2 (long) isoform.

(Dobens et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
UASt
Encoded product / tool
bun
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of bunA.Scer\UAS under the control of Scer\GAL4esg-NP5130 (in combination with a Gal80[ts] transgene to restrict expression to the adult stage) does not significantly affect proliferation or cell number in the midgut.

      (Nie et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      bunA.UAS, Scer\GAL4ap-md544 is an enhancer of wing phenotype of S6kUAS.cMa, Scer\GAL4ap-md544

      (Gluderer et al., 2008)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of bunA.Scer\UAS and MadmScer\UAS.cGa under the control of Scer\GAL4esg-NP5130 (in combination with a Gal80[ts] transgene to restrict expression to the adult stage) leads to a significant increase in cell proliferation in the midgut, and an increase in the number of midgut cells, as compared to controls or flies expressing either construct alone.

      (Nie et al., 2015)

      Co-expression of bunA.Scer\UAS enhances the bent down wing phenotype caused by expression of S6kScer\UAS.cMa under the control of Scer\GAL4ap-md544.

      (Gluderer et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      bun2.Scer\UAS
      bun2.UAS
      bunA.Scer\UAS
      bunA.UAS
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0221062
      • FBal0103885
      References (6)