Tools
Tools Overview & Help
Query by symbols/IDs
Batch Download
Sequence Downloader
ID Validator
Feature Mapper
Search/Browse Portals
QuickSearch
Vocabularies
QueryBuilder
CytoSearch
Interactions Browser
ImageBrowse
Genomics Tools
BLAST
JBrowse
CytoSearch
Feature Mapper
Chromosome Maps
Coordinates Converter
Sequence Downloader
modENCODE RNA-Seq
Overview
RNA-Seq Similarity
RNA-Seq Profile
RNA-Seq By Region
JBrowse
Submit Data
Fast-Track Your Paper
Submit Personal Communication
Feedback on Gene Snapshots
Downloads
Overview
Current Release
Archived Data
Map Conversion
FTP Site:
Releases (FTP)
Genomes (FTP)
Links
External Resources
Model Organisms (MODs)
Alliance of Genome Resources
BeeBase
DictyBase
EcoCyc
Gramene
MGI
PomBase
Pseudobase
RGD
SGD
TAIR
VectorBase
WormBase
Xenbase
ZFIN
Stock Collections
Bloomington Drosophila Stock Center (BDSC)
FlyORF
Korea Drosophila Resource Center (KDRC)
Kyoto Stock Center
NIG-FLY
Tsinghua Fly Center (THFC)
Vienna Drosophila Resource Center (VDRC)
BDGP
DGRC
DRSC/TRiP
DIS by issue
FlyBook
FlyExpress
Interactive Fly
Virtual Fly Brain
FlyCyc
Community
Fast-Track Your Paper
FlyBase Community
Advisory Group
Fly Lab List
Recent Papers With
Technical Advances
Gene Snapshots
FlyBase Forum
Newsletter
FlySlack Community
Mastodon
Bluesky
X (formerly Twitter)
Fly Board
NIH Funding
Species
Phylogeny
Sequenced Species
Synteny Table
Color Illustrations
About
Release Notes
New In This Release
Release Schedule
FlyBase Positions
Citing FlyBase
FlyBase Licensing
FlyBase Consortium
FlyBase Publications
FlyBase Presentations
Grants Supporting FlyBase
Help
Contact FlyBase
FlyBase Wiki:
Help Index
Tool help
Report help
FlyBase FAQ
Info for Authors
Author guidelines
Citing FlyBase
Fast-Track Your Paper Help
Gene Snapshots
Personal communications
Linking to/from FlyBase
Nomenclature
Curation documentation
Controlled Vocabularies in FlyBase
Gene Model Annotation
Gene Ontology (GO) Annotation
Nontraditional alleles
Vectors & Constructs
New to Flies?
Video Tutorials
FlyBase For Developers
Transgenic product class in Gene Reports
DIOPT Version 9.1 Update
Fly Lab List
Previous
Next
FB2024_02
,
released April 23, 2024
Tools
Tools Overview & Help
Query by symbols/IDs
Batch Download
Sequence Downloader
ID Validator
Feature Mapper
Search/Browse Portals
QuickSearch
Vocabularies
QueryBuilder
CytoSearch
Interactions Browser
ImageBrowse
Genomics Tools
BLAST
JBrowse
CytoSearch
Feature Mapper
Chromosome Maps
Coordinates Converter
Sequence Downloader
modENCODE RNA-Seq
Overview
RNA-Seq Similarity
RNA-Seq Profile
RNA-Seq By Region
JBrowse
Submit Data
Fast-Track Your Paper
Submit Personal Communication
Feedback on Gene Snapshots
Downloads
Overview
Current Release
Archived Data
Map Conversion
FTP Site:
Releases (FTP)
Genomes (FTP)
Links
External Resources
Model Organisms (MODs)
Alliance of Genome Resources
BeeBase
DictyBase
EcoCyc
Gramene
MGI
PomBase
Pseudobase
RGD
SGD
TAIR
VectorBase
WormBase
Xenbase
ZFIN
Stock Collections
Bloomington Drosophila Stock Center (BDSC)
FlyORF
Korea Drosophila Resource Center (KDRC)
Kyoto Stock Center
NIG-FLY
Tsinghua Fly Center (THFC)
Vienna Drosophila Resource Center (VDRC)
BDGP
DGRC
DRSC/TRiP
DIS by issue
FlyBook
FlyExpress
Interactive Fly
Virtual Fly Brain
FlyCyc
Community
Fast-Track Your Paper
FlyBase Community
Advisory Group
Fly Lab List
Recent Papers With
Technical Advances
Gene Snapshots
FlyBase Forum
Newsletter
FlySlack Community
Mastodon
Bluesky
X (formerly Twitter)
Fly Board
NIH Funding
Species
Phylogeny
Sequenced Species
Synteny Table
Color Illustrations
About
Release Notes
New In This Release
Release Schedule
FlyBase Positions
Citing FlyBase
FlyBase Licensing
FlyBase Consortium
FlyBase Publications
FlyBase Presentations
Grants Supporting FlyBase
Help
Contact FlyBase
FlyBase Wiki:
Help Index
Tool help
Report help
FlyBase FAQ
Info for Authors
Author guidelines
Citing FlyBase
Fast-Track Your Paper Help
Gene Snapshots
Personal communications
Linking to/from FlyBase
Nomenclature
Curation documentation
Controlled Vocabularies in FlyBase
Gene Model Annotation
Gene Ontology (GO) Annotation
Nontraditional alleles
Vectors & Constructs
New to Flies?
Video Tutorials
FlyBase For Developers
Transgenic product class in Gene Reports
DIOPT Version 9.1 Update
Fly Lab List
Previous
Next
FB2024_02
,
released April 23, 2024
Gene Group: METHYLTRANSFERASES
J2G
Search
Go
Open
Close
General Information
Name
METHYLTRANSFERASES
Species
D. melanogaster
Symbol
METH
FlyBase ID
FBgg0001159
Date last reviewed
2019-04-15
Number of members
127
Description
Description
Methyltransferases catalyze the addition of one or more methyl groups to substrates like protein, DNA, RNA and small molecules. (Adapted from
PMID:26652298
).
Notes on Group
Source Material
The METHYLTRANSFERASES Gene Group has been compiled using the following publication(s):
Jiang et al., 2017
,
Haussmann et al., 2016
,
Calpena et al., 2015
,
Wang et al., 2015
,
Shilatifard, 2012
,
Villar-Garea et al., 2012
,
Wang and Li, 2012
,
Mohan et al., 2011
,
Schaefer et al., 2010
,
Thompson and Travers, 2008
,
Mis et al., 2006
,
Dillon et al., 2005
,
Boulanger et al., 2004
, and
Schotta et al., 2004
.
Key Gene Ontology (GO) terms
Molecular Function
methyltransferase activity
Biological Process
Cellular Component
Enzymatic activity
Enzyme name (EC)
2.1.1.-
Related Gene Groups
Parent group(s)
ONE-CARBON GROUP TRANSFERASES
Component group(s)
DNA METHYLTRANSFERASES
PROTEIN METHYLTRANSFERASES
RNA METHYLTRANSFERASES
UNCLASSIFIED METHYLTRANSFERASES
Members (127)
For all members:
View Orthologs
Export to HitList
Export to Batch Download
GO ribbon stack
molecular function
biological process
cellular component
×
body
Unable to display GO ribbon stack for gene groups with more than 100 members.
DNA METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Mt2
Methyltransferase 2
Dnmt2, dDnmt2, DNMT, DNA methyltransferase 2
(
FlyBase, 2017-
,
Schaefer et al., 2010
)
MRNA METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
aft
adrift
(
FlyBase, 2017-
)
Cmtr1
Cap methyltransferase 1
(
FlyBase, 2017-
)
Mettl3
Methyltransferase like 3
Ime4, Inducer of meiosis 4
(
FlyBase, 2017-
,
Haussmann et al., 2016
)
Rnmt
RNA guanine-7 methyltransferase
l(2)br9, l(2)35Bd, br9, BG:DS00929.5
(
FlyBase, 2017-
)
PROTEIN ARGININE N-METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Art1
Arginine methyltransferase 1
DART1, PRMT1
(
Wang et al., 2015
,
Wang and Li, 2012
,
Boulanger et al., 2004
)
Art2
Arginine methyltransferase 2
DART2
(
Wang et al., 2015
,
Boulanger et al., 2004
)
Art3
Arginine methyltransferase 3
DART3
(
Wang et al., 2015
,
Wang and Li, 2012
,
Boulanger et al., 2004
)
Art4
Arginine methyltransferase 4
DART4, Carmer
(
Wang et al., 2015
,
Wang and Li, 2012
,
Boulanger et al., 2004
)
Art6
Arginine methyltransferase 6
DART6
(
Wang et al., 2015
,
Boulanger et al., 2004
)
Art7
Arginine methyltransferase 7
DART7
(
Wang et al., 2015
,
Wang and Li, 2012
,
Boulanger et al., 2004
)
Art8
Arginine methyltransferase 8
DART8
(
Wang et al., 2015
,
Villar-Garea et al., 2012
,
Boulanger et al., 2004
)
Art9
Arginine methyltransferase 9
DART9
(
Wang et al., 2015
,
Boulanger et al., 2004
)
CG17726
(
FlyBase, 2017-
)
CG32152
(
FlyBase, 2017-
)
csul
capsuleen
dart5, dPRMT5, JBP1, PRMT5
(
Wang et al., 2015
,
Wang and Li, 2012
,
Boulanger et al., 2004
)
PROTEIN CARBOXYL O-METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG3793
BG:DS09217.4
(
FlyBase, 2017-
)
Icmt
Isoprenylcysteine carboxyl methyltransferase
ste14, Dmel\Ste14
(
FlyBase, 2017-
)
Pcmt
Protein-L-isoaspartate (D-aspartate) O-methyltransferase
Pimt
(
FlyBase, 2017-
)
PROTEIN-GLUTAMINE N-METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG10909
(
FlyBase, 2017-
)
Fib
Fibrillarin
(
FlyBase, 2017-
)
RRNA METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG3527
(
FlyBase, 2017-
)
CG7137
(
FlyBase, 2017-
)
CG7544
(
FlyBase, 2017-
)
CG8545
(
FlyBase, 2017-
)
CG8939
(
FlyBase, 2017-
)
CG10903
(
FlyBase, 2017-
)
CG10909
(
FlyBase, 2017-
)
CG11837
(
FlyBase, 2017-
)
CG12863
(
FlyBase, 2017-
)
CG14100
(
FlyBase, 2017-
)
CG14683
(
FlyBase, 2017-
)
Fib
Fibrillarin
(
FlyBase, 2017-
)
l(2)10685
lethal (2) 10685
(
FlyBase, 2017-
)
Mettl5
Methyltransferase like 5
(
FlyBase, 2017-
)
Mrm2
Mitochondrial rRNA methyltransferase 2
(
FlyBase, 2017-
)
mtTFB1
Mitochondrial Transcription Factor B1
d-mtTFB1
(
FlyBase, 2017-
)
mtTFB2
mitochondrial transcription factor B2
d-mtTFB2, TFB2
(
FlyBase, 2017-
)
Nsun5
Nop2/Sun-like domain containing protein 5
(
FlyBase, 2017-
)
SET AND MYND DOMAIN FAMILY
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Smyd3
SET and MYND domain containing, class 3
EG:BACR7C10.4, Bzd, Buzidau
(
Calpena et al., 2015
)
Smyd4-1
SET and MYND domain containing, class 4, member 1
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
,
Schotta et al., 2004
)
Smyd4-2
SET and MYND domain containing, class 4, member 2
Smyd4, dSmyd4
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
)
Smyd4-3
SET and MYND domain containing, class 4, member 3
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
)
Smyd4-4
SET and MYND domain containing, class 4, member 4
BcDNA:LD29892
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
)
Smyd5
SET and MYND domain containing, class 5
(
FlyBase, 2017-
,
Jiang et al., 2017
,
Calpena et al., 2015
,
Schotta et al., 2004
)
SmydA-1
SET and MYND domain containing, arthropod-specific, member 1
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
)
SmydA-2
SET and MYND domain containing, arthropod-specific, member 2
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
)
SmydA-3
SET and MYND domain containing, arthropod-specific, member 3
(
Jiang et al., 2017
,
Calpena et al., 2015
)
SmydA-4
SET and MYND domain containing, arthropod-specific, member 4
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
)
SmydA-5
SET and MYND domain containing, arthropod-specific, member 5
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
)
SmydA-6
SET and MYND domain containing, arthropod-specific, member 6
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
,
Schotta et al., 2004
)
SmydA-7
SET and MYND domain containing, arthropod-specific, member 7
(
Jiang et al., 2017
,
Calpena et al., 2015
)
SmydA-8
SET and MYND domain containing, arthropod-specific, member 8
msta, EG:103B4.4
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
,
Schotta et al., 2004
)
SmydA-9
SET and MYND domain containing, arthropod-specific, member 9
lincRNA.971
(
Jiang et al., 2017
,
Calpena et al., 2015
,
Thompson and Travers, 2008
,
Schotta et al., 2004
)
SET DOMAIN LYSINE METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
ash1
absent, small, or homeotic discs 1
ash-1, dash, absent, small or homeotic discs 1, ash
(
Jiang et al., 2017
,
Dillon et al., 2005
,
Schotta et al., 2004
)
CG4565
(
Jiang et al., 2017
,
Schotta et al., 2004
)
E(z)
Enhancer of zeste
EZ, pco, l(3)1902, Su(z)301, polycombeotic
(
Jiang et al., 2017
,
Dillon et al., 2005
,
Schotta et al., 2004
)
egg
eggless
dSETDB1, SetDB1, DmSetdb1, dEset
(
Jiang et al., 2017
,
Mis et al., 2006
,
Schotta et al., 2004
)
G9a
G9a
dG9a, EG:BACR37P7.2, EHMT
(
Jiang et al., 2017
,
Mis et al., 2006
,
Schotta et al., 2004
)
Hmt4-20
Histone methyltransferase 4-20
Suv4-20, Su(var)4-20, EG:115C2.10
(
Jiang et al., 2017
,
Dillon et al., 2005
,
Schotta et al., 2004
)
NSD
Nuclear receptor binding SET domain protein
Mes-4, dMes-4
(
Jiang et al., 2017
,
Schotta et al., 2004
)
Set1
SET domain containing 1
dSet1
(
Jiang et al., 2017
,
Shilatifard, 2012
,
Mohan et al., 2011
)
Set2
SET domain containing 2
dSet2, dHypb
(
Jiang et al., 2017
,
Schotta et al., 2004
)
Set8
SET domain containing 8
PR-Set7, l(3)neo41, Set7, dSet8
(
Jiang et al., 2017
,
Dillon et al., 2005
,
Schotta et al., 2004
)
Setd3
SET domain containing 3
(
FlyBase, 2017-
,
Jiang et al., 2017
,
Schotta et al., 2004
)
Su(var)3-9
Suppressor of variegation 3-9
SuVar3-9, Su-var(3)9, ptn, SUV39
(
Jiang et al., 2017
,
Mis et al., 2006
,
Dillon et al., 2005
,
Schotta et al., 2004
)
trr
trithorax-related
EG:63B12.3
(
Jiang et al., 2017
,
Shilatifard, 2012
,
Mohan et al., 2011
,
Schotta et al., 2004
)
trx
trithorax
l(3)j14A6, trxG, l(3)s5452, Trx-C, DMTRXIII
(
Jiang et al., 2017
,
Shilatifard, 2012
,
Mohan et al., 2011
,
Dillon et al., 2005
,
Schotta et al., 2004
)
TRNA METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Alkbh8
AlkBh8 tRNA methyltransferase
(
FlyBase, 2017-
)
CG1074
(
FlyBase, 2017-
)
CG4045
EG:22E5.4
(
FlyBase, 2017-
)
CG9386
(
FlyBase, 2017-
)
CG12822
(
FlyBase, 2017-
)
CG18048
(
FlyBase, 2017-
)
CG18596
(
FlyBase, 2017-
)
CG18853
(
FlyBase, 2017-
)
CG32281
(
FlyBase, 2017-
)
CG34195
(
FlyBase, 2017-
)
fid
fire dancer
(
FlyBase, 2017-
)
Mettl2
Methyltransferase like 2
metl
(
FlyBase, 2017-
)
Mt2
Methyltransferase 2
Dnmt2, dDnmt2, DNMT, DNA methyltransferase 2
(
FlyBase, 2017-
)
Nsun2
NOP2-Sun domain family, member 2
(
FlyBase, 2017-
)
Nsun6
NOP2/Sun RNA methyltransferase 6
(
FlyBase, 2017-
)
rswl
roswell
MRPP1
(
FlyBase, 2017-
)
Trm1
tRNA methyltransferase 1
(
FlyBase, 2017-
)
Trm7-32
tRNA methyltransferase 7-32
dTrm7_32
(
FlyBase, 2017-
)
Trm7-34
tRNA methyltransferase 7-34
dTrm7_34
(
FlyBase, 2017-
)
Trmt2a
tRNA methyltransferase 2a
(
FlyBase, 2017-
)
Trmt10A
tRNA methyltransferase 10A
(
FlyBase, 2017-
)
Trmt61
tRNA methyltransferase 61
(
FlyBase, 2017-
)
UNCLASSIFIED METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Bhmt
Betaine-homocysteine S-methyltransferase
(
FlyBase, 2017-
)
CG2906
(
FlyBase, 2017-
)
CG8067
(
FlyBase, 2017-
)
CG10621
selenocysteine methyltransferase
(
FlyBase, 2017-
)
CG11596
EG:39E1.1
(
FlyBase, 2017-
)
CG13126
(
FlyBase, 2017-
)
CG18661
(
FlyBase, 2017-
)
CG33964
(
FlyBase, 2017-
)
Coq3
Coenzyme Q3
(
FlyBase, 2017-
)
Coq5
Coenzyme Q5
(
FlyBase, 2017-
)
Gnmt
Glycine N-methyltransferase
(
FlyBase, 2017-
)
jhamt
juvenile hormone acid methyltransferase
BG:DS09218.5, DmJHAMT
(
FlyBase, 2017-
)
Ts
Thymidylate synthase
(
FlyBase, 2017-
)
UNCLASSIFIED PROTEIN-LYSINE N-METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG2614
38D.29
(
FlyBase, 2017-
)
CG3337
(
FlyBase, 2017-
)
CG5013
(
FlyBase, 2017-
)
CG5466
(
FlyBase, 2017-
)
CG7889
(
FlyBase, 2017-
)
CG9154
(
FlyBase, 2017-
)
CG9643
(
FlyBase, 2017-
)
CG10947
38C.42
(
FlyBase, 2017-
)
CG33230
(
FlyBase, 2017-
)
gpp
grappa
l(3)03342
(
FlyBase, 2017-
)
ham
hamlet
(
FlyBase, 2017-
)
Lpt
Lost PHDs of trr
cmi, cara mitad
(
FlyBase, 2017-
)
UNCLASSIFIED PROTEIN METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
agt
O-6-alkylguanine-DNA alkyltransferase
(
FlyBase, 2017-
)
CG5339
(
FlyBase, 2017-
)
CG10584
(
FlyBase, 2017-
)
CG17219
(
FlyBase, 2017-
)
Dph5
Diphthamide methyltransferase
l(3)L4910
(
FlyBase, 2017-
)
HemK1
HemK methyltransferase 1
(
FlyBase, 2017-
)
HemK2
HemK methyltransferase 2
(
FlyBase, 2017-
)
Ntmt
N-terminal methyltransferase
(
FlyBase, 2017-
)
UNCLASSIFIED RNA METHYLTRANSFERASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Amus
Another methylase of U6
(
FlyBase, 2017-
)
bin3
bicoid-interacting protein 3
(
FlyBase, 2017-
)
CG11342
(
FlyBase, 2017-
)
CG12128
(
FlyBase, 2017-
)
Hen1
Hen1 methyltransferase
Pimet, piRNA methyltransferase, DmHen1
(
FlyBase, 2017-
)
Mettl4
Methyltransferase like 4
ORF2
(
FlyBase, 2017-
)
Tgs1
Trimethylguanosine synthase 1
dtl, tat-like, l(3)S096713, Drosophila Tat-like, dTgs1
(
FlyBase, 2017-
)
External Data
Equivalent Group(s)
Human Methyltransferase families (HGNC)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
METH
METHYLTRANSFERASES
Secondary FlyBase ID(s)
References (16)
Report Sections
Open
Close
General Information
Description
Members
External Data
Synonyms and Secondary IDs
References