Med29
Please see the JBrowse view of Dmel\ix for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Component of the Mediator complex (By similarity). Self-associates. Interacts with dsx.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ix using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\ix in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
ix is required for complete differentiation of female but not male specific adult cuticular structures.
Levels of haemolymph vitellogenin of ix flies tentatively suggest ix gene function is neither required for vitellogenin synthesis nor for maintaining proper level of dosage compensation of yolk protein genes. In ix mutant males the yolk protein gene expression is further repressed which suggests the gene is inactive at least in the fat body cells of the males.
At the morphological level, a loss of ix+ function results in the simultaneous realization of both male and female developmental pathways in diplo-X individuals. The ix product is required to function with the female-specific product of dsx to implement appropriate female sexual differentiation in diplo-X individuals. ix does not have a role in sexual behaviour in haplo-X individuals. Clonal analysis suggests that ix functions in a cell-autonomous manner in the abdomen and that it is required in the abdominal histoblasts after the resumption of cell division at pupariation for the normal sexual development of the abdominal tergites.
ix plays no role in the development of sexually dimorphic skeletal muscles.
Source for merge of: ix CG13201
Source for merge of ix CG13201 was sequence comparison ( date:021108 ).