TFIIA, dTFIIA
Please see the JBrowse view of Dmel\TfIIA-L for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
1.8 (northern blot)
None of the polypeptides share 100% sequence identity.
366 (aa); 39 (kD predicted)
Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (Tafs). TFIIA is a heterodimer of a unprocessed large subunit 1 and a small subunit gamma. It was originally believed to be a heterotrimer of an alpha (p30), a beta (p20) and a gamma subunit (p14). Interacts with Tbp. Taf4 interacts with TFIIA-L when TFIIA-L is in complex with Tbp.
The precursor form (48 kDa) is cleaved to give rise to the alpha (30 kDa) and beta (20 kDa) subunits.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\TfIIA-L using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
JBrowse - Visual display of RNA-Seq signals
View Dmel\TfIIA-L in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
New stable cell line derived from S2-Invitrogen : The following derivative cell lines were generated: Parental OsTir-expressing S2 cell line, Trf2 C-terminally-tagged AID S2 cell line, Tbp-N-terminally-tagged AID S2 cell line, Dref-N-terminally-tagged AID S2 cell line, TfIIA-L-C-terminally-tagged AID S2 cell line, Chro-N-terminally-tagged AID S2 cell line.